Evaluation of factors related to depression in peritoneal dialysis patients: a multicenter cross-sectional study

Abstract

Background End-stage renal disease (ESRD) is serious global public health challenge in many developing countries. Treatment of ESRD is carried out through renal replacement therapy like peritoneal dialysis (PD). Depression is the most common mood disorder which has a strong impact on the quality of life in patients with ESRD. Little is known about the prevalence and risk factors of depression in peritoneal dialysis patients. Method and materials A multicenter cross-sectional study was conducted on 164 adult ESRD patients undergoing peritoneal dialysis for at least three months who referred to the peritoneal dialysis centers of Al-Zahra, Noor & Ali Asghar hospitals, Isfahan, Iran from May to August 2019. Beck Depression Inventory Second Edition questionnaire was used to measure the symptoms of depression and its severity. Results 43.5% of patients had some levels of depression. Assessing the association of depression with demographic and PD-related factors showed that there was no significant difference regarding age, BMI, dialysis adequacy and residual kidney function, dialysis frequency, type of dialysis solution used, disease duration, and age at the start of dialysis. Ordinal logistics regression analysis showed significant association between depression severity categories and gender (OR = 0.397, CI: 0.160–0.985, p = 0.046), marital status (OR = 2.983, CI: 1.180–7.541, p = 0.021), having a separate room for dialysis (OR = 2.511, CI: 1.108–5.692, p = 0.027). Conclusion As our findings have revealed 43.5% of our participants suffered from mild-to-severe depression, we suggest careful attention and routine evaluation for depression in PD patients, especially women and single patients and those who have low socioeconomic status.

The utilization of renal dialysis: a comprehensive study in Saudi Arabia

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Anxiety and depression in geriatric hemodialysis patients: factors that influence the border of diseases

“…Fernandez et al, reported that if the prevalence of depression and anxiety is compared between the general population and HD patients, the latter will definitely have a greater prevalence of these two mental diseases (Fernandez et al, 2022). Various studies found a different incidence of depression among dialysis patients (Dong et al, 2016;Bazazzadeh et al, 2023). Based on data from the World Health Organization (WHO), worldwide prevalence rates of depression and anxiety in 2015 have been determined to be 4.4 and 3.6%, respectively (World Health Organization, 2017).…”

Combined influence of depression and low-grade inflammation on mortality in peritoneal dialysis patients

“…What’s more, most depression patients are easily ignored and inadequately treated in the past decade. Previous studies only assessed the relationship of depression and PD patients at the baseline [ 16 ]. In addition, published evidence that examined depression levels impacting clinical outcome including mortality risk, has only included patients on hemodialysis [ 12 ].…”