Evaluation of exhaled breath temperature (EBT) as a marker and predictor of asthma exacerbation in children and adolescents

Wojsyk‐Banaszak, Irena; Mikoś, Marcin; Szczepankiewicz, Aleksandra; Wielebska, Alicja; Sobkowiak, Paulina; Kamińska, Aleksandra; Bręborowicz, Anna

doi:10.1080/02770903.2017.1290104

Cited by 9 publications

(7 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies demonstrated that in asthma EBT is related to the degree of airway inflammation [ 47 ], it increases in uncontrolled asthma and decreases in response to anti-inflammatory treatment [ 48 , 50 ], it is significantly higher in patients with severe asthma compared to those with mild to moderate asthma [ 51 ] and it reflects changes in airway inflammation in children with virus-induced asthma exacerbations [ 52 ]. In contrast, other studies found no relationship between EBT and measures of asthma control [ 53 ].…”

Section: Exhaled Breath Temperature (Ebt)mentioning

confidence: 99%

Exhaled biomarkers in childhood asthma: old and new approaches

Ferraro

Carraro

Bozzetto

et al. 2018

asthma res and pract

View full text Add to dashboard Cite

BackgroundAsthma is a chronic condition usually characterized by underlying inflammation. The study of asthmatic inflammation is of the utmost importance for both diagnostic and monitoring purposes. The gold standard for investigating airway inflammation is bronchoscopy, with bronchoalveolar lavage and bronchial biopsy, but the invasiveness of such procedures limits their use in children. For this reason, in the last decades there has been a growing interest for the development of noninvasive methods.Main bodyIn the present review, we describe the most important non-invasive methods for the study of airway inflammation in children, focusing on the measure of the fractional exhaled nitric oxide (feNO), on the measure of the exhaled breath temperature (EBT) and on the analysis of both exhaled breath condensate (EBC) and exhaled air (Volatile Organic Compounds, VOCs), using targeted and untargeted approaches. We summarize what is currently known on the topic of exhaled biomarkers in childhood asthma, with a special emphasis on emerging approaches, underlining the role of exhaled biomarkers in the diagnosis, management and treatment of asthma, and their potential for the development of personalized treatments.ConclusionAmong non-invasive methods to study asthma, exhaled breath analysis remains one of the most interesting approaches, feNO and “-omic” sciences seem promising for the purpose of characterizing biomarkers of this disease.

show abstract

Section: Exhaled Breath Temperature (Ebt)mentioning

confidence: 99%

Exhaled biomarkers in childhood asthma: old and new approaches

Ferraro

Carraro

Bozzetto

et al. 2018

asthma res and pract

View full text Add to dashboard Cite

show abstract

“…This is the first study to sequentially measure the EBT at three distinct stages, namely the onset of an asthma attack, during the recovery period, and after patients achieved a stable state; the present study is also the first to compare subjects' symptomatology and pulmonary function during these same three time periods. [34][35][36] In conclusion, this study showed that the EBT can be used to assess a pediatric patient's recovery from an asthma attack. Therefore, children with asthma attacks should be encouraged to use exhaled breath thermometers to clinically aid in the maintenance of asthma control and in therapeutic management.…”

Section: Discussionmentioning

confidence: 86%

“…The main strength of our study was that it longitudinally measured the PLET in children who experienced asthma attacks from their initial admission until 1 month after discharge. This is the first study to sequentially measure the EBT at three distinct stages, namely the onset of an asthma attack, during the recovery period, and after patients achieved a stable state; the present study is also the first to compare subjects’ symptomatology and pulmonary function during these same three time periods …”

Section: Discussionmentioning

confidence: 91%

Exhaled breath temperature as a tool for monitoring asthma control after an attack in children

Sol

Kim

et al. 2019

Pediatric Pulmonology

View full text Add to dashboard Cite

Background Exhaled breath temperature (EBT) has been suggested as a non‐invasive marker of airway inflammation in asthma. There have been no studies examining longitudinal changes in EBT following asthma attacks. Objective To investigate changes in EBT during and after an asthma attack and to relate these changes to changes in respiratory physiological measurements. Methods We evaluated 38 hospitalized children aged 5‐18 years diagnosed with an asthma attack. Spirometry was performed upon hospitalization. During hospitalization, EBT, peak expiratory flow rate (PEFR), and asthma score were measured daily. These tests were repeated 1 week and 1 month after discharge. The overall PEFR change, temporal changes in plateau values at the end of expiration, and time‐dynamic associations were evaluated using linear mixed models. Results FEV1 was lower at admission than at discharge (63.3 ± 24 vs 99.5 ± 14 percent of predicted, P < 0.001). The EBT was higher at admission than at 1 week after discharge (34.1°C [range: 33.9‐34.8°C] vs 33.6°C [range: 33.0‐34.2°C], P = 0.007); overall, EBTs decreased over time (P = 0.007). Among individual subjects, decreased EBT was correlated with increased PEFR over time. Furthermore, plateau values at the end of expiration had a time‐dependent, dynamic association with the PEFR during hospitalization (P = 0.005) and between asthma attack onset and asthma status stabilization (P = 0.032). Conclusions The EBT was elevated during asthma attacks and gradually decreased until asthma was well controlled. The EBT may be a useful, non‐invasive tool for monitoring asthma control in children.

show abstract

“…The hydrogel sensor was installed on a smooth platform and kept at a distance of 5 cm to record the change in sensor resistance as the hydrogel was exhaled. When the room temperature is 19-25°C and the humidity is 30%-60%, the temperature of the exhaled gas is about 32.3°C, which is higher than the surface temperature of the gel [32]. As shown in Fig.…”

Section: Science China Materialsmentioning

confidence: 88%

Facile preparation and high performance of wearable strain sensors based on ionically cross-linked composite hydrogels

et al. 2020

View full text Add to dashboard Cite

Evaluation of exhaled breath temperature (EBT) as a marker and predictor of asthma exacerbation in children and adolescents

Abstract: We suggest that EBT may serve as marker and predictor of asthma exacerbation in children. EBT follow-up may be useful in asthma monitoring in children and adolescents.

Cited by 9 publications

References 20 publications

Exhaled biomarkers in childhood asthma: old and new approaches

Exhaled biomarkers in childhood asthma: old and new approaches

Exhaled breath temperature as a tool for monitoring asthma control after an attack in children

Facile preparation and high performance of wearable strain sensors based on ionically cross-linked composite hydrogels

Contact Info

Product

Resources

About