Evaluation of endothelial function in patients with Behçet’s disease in remission: A cross-sectional study

Rodrigues, F.M.; Bacchiega, Ana Beatriz; Bacchiega, Bruno Cesar; Ochtrop, Manuella Lima Gomes; Levy, Roger A.

doi:10.5152/eujrheum.2022.20184

Cited by 4 publications

(4 citation statements)

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“…Inhibition of NF-kB activity suppresses interlukin-6 (IL-6), VCAM-1 and MCP-1 expression [ 89 ]. Many studies have shown that inflammation may play a role in vascular injury [ 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ]. The presence of angiotensin II, oxidized LDL, and inflammatory cytokines activates NADPH oxidase, which in turn induces inflammation under the condition of oxidative stress due to excess ROS.…”

Section: Inflammationmentioning

confidence: 99%

“…Not only in experimental animal models but also in humans, vascular endothelial dysfunction caused by chronic inflammation seems to play an important role in the pathogenesis of atherosclerosis. Clinical studies have suggested an association between chronic inflammation and vascular function [ 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ].…”

Section: Inflammationmentioning

confidence: 99%

“…Several lines of evidence have shown that other acute and chronic inflammatory diseases are also associated with endothelial dysfunction [ 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ], though the mechanisms of endothelial dysfunction in acute and chronic inflammatory diseases remain unclear. Endothelial function is impaired in various acute inflammatory diseases including acute rheumatic fever [ 104 ], systemic inflammation induced by influenza A vaccination in patients with human immunodeficiency virus infection [ 105 ], pre-eclampsia [ 106 ], acute Kawasaki disease [ 107 ], severe sepsis [ 108 ], and foot-and-mouth disease [ 109 ] and in various chronic inflammatory diseases including rheumatoid arthritis [ 110 , 111 ], juvenile idiopathic arthritis [ 112 ], systemic sclerosis [ 113 ], systemic lupus erythematosus [ 114 ], Behçet’s disease [ 115 ], rhinosinusitis [ 116 ], ankylosing spondylitis [ 117 ], multiple sclerosis [ 118 ], bowel disease [ 119 ], Takayasu disease [ 120 ], psoriasis […”

Section: Inflammationmentioning

confidence: 99%

“…The results confirm the existence of a process leading from acute and chronic inflammation to vascular endothelial dysfunction in humans, as shown in patients with Helicobacter pylori infection, patients with periodontal disease, patients with Kawasaki disease, patients with Bürger’s disease, and other inflammatory diseases [ 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 ]. Vascular endothelial function may be considered a marker of vascular inflammation, although various chemical biomarkers exist for inflammation.…”

Section: Inflammationmentioning

confidence: 99%

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Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Higashi

2022

Antioxidants

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Oxidative stress and chronic inflammation play an important role in the pathogenesis of atherosclerosis. Atherosclerosis develops as the first step of vascular endothelial dysfunction induced by complex molecular mechanisms. Vascular endothelial dysfunction leads to oxidative stress and inflammation of vessel walls, which in turn enhances vascular endothelial dysfunction. Vascular endothelial dysfunction and vascular wall oxidative stress and chronic inflammation make a vicious cycle that leads to the development of atherosclerosis. Simultaneously capturing and accurately evaluating the association of vascular endothelial function with oxidative stress and inflammation would be useful for elucidating the pathophysiology of atherosclerosis, determining treatment efficacy, and predicting future cardiovascular complications. Intervention in both areas is expected to inhibit the progression of atherosclerosis and prevent cardiovascular complications.

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Section: Inflammationmentioning

confidence: 99%

Section: Inflammationmentioning

confidence: 99%

Section: Inflammationmentioning

confidence: 99%

Section: Inflammationmentioning

confidence: 99%

See 2 more Smart Citations

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Higashi

2022

Antioxidants

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Subclinical atherosclerosis in Behcet’s disease and its inverse relation to azathioprine use: an updated meta-analysis

et al. 2023

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The Functions of the Brazil Federal Court of Accounts in the Improvement of Public Administration

Menezes de Carvalho

2024

IJMSBA

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This article aims to analyze the control benefits exercised by the Brazil Federal Court of Accounts – TCU to improve Public Administration, considering that an extensive range of studies has been developed on public efficiency, but without considering the aspect of control as an essential instrument of this transformation, and also by the fact that the Federal Executive Power has sometimes exposed the TCU as an impediment to the development of the country From a methodological approach qualitative, exploratory, with the use of literature and document analysis, the barriers to an efficient public administration and the functions performed by the TCU were analyzed. Thus, it was evidenced that public efficiency can be achieved by tackling impediments to an efficient model identified in this article by two groups: the Legality of deviations and purpose and improper operation. From this identification, the type of control exercised by TCU was presented according to its legal powers, the focus of its operations, and the resulting benefits, which were also presented in financial and operational groups. Thus, it was concluded that the benefits generated by TCU’s actions work in fighting impediments to efficient public Administration, consequently contributing to improving the federal public Administration.

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Evaluation of endothelial function in patients with Behçet’s disease in remission: A cross-sectional study

Cited by 4 publications

References 0 publications

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Subclinical atherosclerosis in Behcet’s disease and its inverse relation to azathioprine use: an updated meta-analysis

The Functions of the Brazil Federal Court of Accounts in the Improvement of Public Administration

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