Abstract:Summary: EMIT assays for the determination of phenytoin, methotrexate, disopyramide, digoxin and thyroxine were adapted to the Cobas Bio centrifugal analyzer and compared with the corresponding laboratory routine procedures. Evaluation of the data from the Cobas Bio by 5 different mathematical models showed that the fourparameter logit model correlated best with the comparison procedures and the originally recommended calculation model for the reagent lots used in our study. The precision of the EMIT phenytoin… Show more
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