Evaluation of dual p16/Ki‐67 immunostaining on anal cytology specimens
Marie C. Smithgall,
William S. Towne,
Abel A. Gonzalez
et al.
Abstract:IntroductionDual immunostaining for p16/Ki67 is FDA‐approved for use on liquid‐based cervical cytology specimens; however, the utility of dual staining in anal cytology especially for ASCUS risk stratification is not well established.MethodsWe investigated dual staining performance on anal cytology specimens and correlated with subsequent cytologic interpretation, high‐risk HPV status, and anal biopsy results. Dual staining for p16/Ki‐67 was performed on all liquid‐based anal cytology specimens from December 2… Show more
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