Evaluation of dual energy spectral CT in differentiating metastatic from non-metastatic lymph nodes in rectal cancer: Initial experience

Liu, Huanhuan; Yan, Fuhua; Pan, Zhengying; Lin, Xiaozhu; Luo, Xin; Shi, Cen; Chen, Xiaoyan; Wang, Baisong; Zhang, Huan

doi:10.1016/j.ejrad.2014.11.016

Cited by 60 publications

(47 citation statements)

References 29 publications

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“…There has been no specific study on the use of MRI in locating malignancy within perihepatic lymph nodes. MRI is known to have a high soft tissue contrast and should improve detection of disease when size criterion was combined with border and signal morphology of the node [22]. High resolution MRI has the ability to visualize a lymph node as small as 2 mm in diameter [30].…”

Section: Discussionmentioning

confidence: 99%

“…In a paper estimating frequency of perirectal nodal metastasis, the majority of metastasis occurred in lymph nodes smaller than 1 cm [22] [38].…”

Section: Discussionmentioning

confidence: 99%

“…Positron emission tomography (PET) scan is used more frequently these days as a staging tool. Currently, despite multiple modalities being available, there is no diagnostic guideline in aiding a radiologist to differentiate a metastatic lymph node from a non-metastatic one [22] [23] [24] [25].…”

mentioning

confidence: 99%

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Pre-Operative Perihepatic Lymph Node Assessment in Colorectal Cancer Liver Metastasis—A Review of Current Literature

Yong¹,

Burrows²,

Christophi³

2017

OJMI

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Objective: Perihepatic lymph node involvement in colorectal cancer liver metastases is a negative prognostic factor. Resection of certain nodal stations around the liver has been shown to possibly improve survival. The aim of this review is to interrogate current literature on pre-operative investigations in diagnosing lymph node involvement. Method: A systematic review was conducted of articles published since 2006 to determine usefulness of pre-operative imaging in diagnosing lymph node involvement in colorectal cancer liver metastases. Results: Only 2 papers met the inclusion criteria for this study. Computed tomography (CT) scans were found to have sensitivities of 33% and 40%, specificities of 94% and 92%, positive predictive values (PPV) of 56% and 30%, and negative predictive values (NPV) of 85% and 95%. Positron emission tomography (PET) was studied in one of the paper and was found to have sensitivity, specificity, PPV and NPV of 57%, 100%, 100%, and 88% respectively. Conclusion: There is a significant lack of research on pre-operative investigations of perihepatic lymph node involvement in colorectal cancer liver metastases. Pre-operative CT and PET scans in assessing perihepatic lymph nodes were shown to be inaccurate. Newer pre-operative imaging modalities and research would be needed.

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Section: Discussionmentioning

confidence: 99%

“…In a paper estimating frequency of perirectal nodal metastasis, the majority of metastasis occurred in lymph nodes smaller than 1 cm [22] [38].…”

Section: Discussionmentioning

confidence: 99%

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Pre-Operative Perihepatic Lymph Node Assessment in Colorectal Cancer Liver Metastasis—A Review of Current Literature

Yong¹,

Burrows²,

Christophi³

2017

OJMI

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“…Dual energy computed tomography (DECT) has proven its clinical usefulness for tissue characterization over the past years, e.g., in the characterization of bone lesions, renal masses, urinary calculi or coronary plaque components [1][2][3][4][5][6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Dual-energy snap-shot perfusion CT in suspect pulmonary nodules and masses and for lung cancer staging

Sudarski

Hagelstein

Weis

et al. 2015

European Journal of Radiology

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“…However, it remains to be seen whether the FDA and BfArM will approve USPIO contrast agents. Liu et al [91] recently reviewed the value of dual-energy CT in the differentiation of benign and malignant lymph nodes in 55 rectal cancer patients. Compared to only the determination of the short-axis diameter of lymph nodes (SAD), the additional determination of the normalized iodine concentration (NIC) in this collective increased the accuracy of metastasis determination to 83 %.…”

Section: Local Staging Of Rectal Cancermentioning

confidence: 99%

A Review of Scientific Topics and Literature in Abdominal Radiology in Germany – Part 1: Gastrointestinal Tract

Schreyer

Weßling

Kinner

et al. 2015

Fortschr Röntgenstr

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The working group for abdominal and gastrointestinal diagnosis is a group of the German Radiological Society (DRG) focusing clinically and scientifically on the diagnosis and treatment of the gastrointestinal tract with all parenchymatous abdominal organs. In addition to the clinical and scientific further development of abdominal radiology, the education of radiologists within this core discipline of radiology is one of the major aims. In this article we give an up-to-date literature review of scientific radiological topics especially covered by German radiologists. This manuscript focuses on the most recent literature on the diagnosis of the stomach, small bowel, colon and rectum. The review with a focus on the most recent studies published by German radiologists concludes with a synopsis of mesenterial bleeding and ischemia followed by a critical appraisal of the current literature on conventional abdominal radiography. Key Points: ??Based on recent literature and guidelines there is a change of paradigms regarding the diagnosis of esophagus and gastric cancer towards CT, which is considered equally to endosonography. ??For small bowel imaging in Crohn?s disease ultrasound as well as MRI with a new focus on DWI are the most important imaging modalities scientifically. ??For colonic diagnosis virtual colonoscopy has replaced the conventional radiological methods. For staging of rectal carcinoma as well as for therapeutic stratification a high resolution MRI of the pelvis is of paramount interest. ??Multislice CT is considered the most important modality to assess mesenteric ischemia or bleeding. Citation Format: ??Schreyer AG, Wessling J, Kinner S et?al. A Review of Scientific Topics and Literature in Abdominal Radiology in Germany ? Part 1: Gastrointestinal Tract. Fortschr R?ntgenstr 2016; 188: 134???145

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Evaluation of dual energy spectral CT in differentiating metastatic from non-metastatic lymph nodes in rectal cancer: Initial experience

Cited by 60 publications

References 29 publications

Pre-Operative Perihepatic Lymph Node Assessment in Colorectal Cancer Liver Metastasis—A Review of Current Literature

Pre-Operative Perihepatic Lymph Node Assessment in Colorectal Cancer Liver Metastasis—A Review of Current Literature

Dual-energy snap-shot perfusion CT in suspect pulmonary nodules and masses and for lung cancer staging

A Review of Scientific Topics and Literature in Abdominal Radiology in Germany – Part 1: Gastrointestinal Tract

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