Evaluation of DNA-binding, radical scavenging and cytotoxic activity of five coordinated Cd(ii) complexes containing 2-acetylpyridine-N4-substituted thiosemicarbazone

Abstract

Evaluation of DNA-binding, radical scavenging and cytotoxic activity of five coordinated Cd(II) complexes containing 2-acetylpyridine-N 4 -substituted thiosemicarbazone3

Chitosan promotes ROS-mediated apoptosis and S phase cell cycle arrest in triple-negative breast cancer cells: evidence for intercalative interaction with genomic DNA

“…On the other hand, intercalation occurs when small molecules intercalate within the nucleic acid base pairs. 12,14 Berenil, bleomycin and distamycin A (groove binding agents), tamoxifen, doxorubicin, daunomycin, quinolones, and quinoxalines (DNA intercalative agents) 12 are some of the successful therapeutic DNA-interacting agents.…”

Nickel(ii) and copper(ii) complexes constructed with N2S2 hybrid benzamidine–thiosemicarbazone ligand: synthesis, X-ray crystal structure, DFT, kinetico-catalytic and in vitro biological applications

“…Thiosemicarbazones have been chosen to functionalize benzimidoyl chlorides due to their versatile coordination behavior and promising biological and pharmaceutical properties. [12][13][14][15] A new tetradentate chelator has been synthesized from a benzimidoyl chloride moiety and Nmethylthiosemicarbazide (Scheme 1).…”

Ruthenium(II) complexes encompassing 2-oxo-1,2-dihydroquinoline-3-carbaldehyde thiosemicarbazone hybrid ligand: A new versatile potential catalyst for dehydrogenative amide synthesis

“…The multiplets at 7.79-7.09 ppm in the spectra of complexes are assigned to aromatic protons. In addition, the methyl protons appeared at 2.66 ppm [42]. The 13 C NMR spectra of the complexes showed the expected signals in the appropriate regions.…”