Evaluation of diuretic activity of Syzygium cumini and its effect on prostaglandin system

Oberoi

Ann.UDJG.FoodTechnology

et al. 2020

Syzygium cumini (S. cumini) is an underutilized fruit of tropical and subtropical regions with various bioactive compounds distributed in all parts of the plant. The fruit and its by-products, such as seeds, have both nutritional and medicinal value. However, fruit and seeds have not been fully considered as potential functional food ingredients to develop foods with promising health benefits. Based on the available information in the literature, fruit and seed are rich in phytochemicals, such as myricetin, oxalic acid, gallic acid, citronellol, cyanidin diglucoside, hotrienol, phytosterols, flavonoids, carotenoids and polyphenols as well as micronutrients. In addition, they were reported to possess several beneficial health properties. Further, research in this area would provide valuable information for their potential utilization as functional food ingredients. This review presents comprehensive information about the bioactive compounds and nutraceutical properties of S. cumini fruit and seeds, as well as the potential of using them as functional food ingredients

Section: Neuro-psychopharmacological Activitymentioning

confidence: 99%

Bioactive compounds and antioxidant activitity in different extracts of sea buckthorn

Oberoi

Ann.UDJG.FoodTechnology

et al. 2020

“…The effects of 2-hydroxyacetophenone isatin derivatives 97 on cardiac and vascular smooth muscles in rats was reported. Neuropharmacological activity of isatin-3-[N-2-(2-benzalaminothiazol-4-yl)]-hydrazones 98 were reported. Isatin derivatives 99 was reported to act as transthyretin fibrillogenesis inhibitors (TTR Amyloid disease).…”

Section: Other Activitiesmentioning

confidence: 99%

Review of Chemical, Pharmacological, Biological Activities of Isatin and Its Derivatives – Part-2 (2002 To 2020)

2020

JST

: Isatin is a naturally occurring substance identified in humans, animals, plants and coal tar. Isatin derivatives are reported to possess a wide range of activites. This review is in continuation of “Part-1 (1877-2002)” review published by our team. This review encompasses the most signigicant reports published during 2002 to 2020 on the biological & pharmacological activites of isatin and its derivatives. The review includes the various synthetic reactions of isatin and activites reported. The pharmacological and biological activites reported were antimicrobial, antineoplastic & related activities; analgesic, anti-inflammatory, anticonvulsant, antioxidant, activity against veterinary pathogen, effects on cardiac & vascular smooth muscles; transthyretin fibrillogenesis inhibitor and antiglycation activity of isatin compounds.

“…Hypertension, a biomarker of MS, is the most prevalent cause behind CVDs worldwide, and it is also a major risk factor for the development of other diseases such as MS, diabetes, renal dysfunction, congestive heart failure, coronary artery disease, stroke, etc. [ 6 ]. Preeclampsia (PE) is a condition marked by high blood pressure, proteinuria, or edema.…”

Section: Introductionmentioning

confidence: 99%

Astounding Health Benefits of Jamun (Syzygium cumini) toward Metabolic Syndrome

et al. 2022

Syzygium cumini, also called Jamun, or black plum, is an excellent source of bioactive components such as flavonoids, polyphenols, antioxidants, iron, and vitamin C. The Jamun tree is a tropical evergreen blooming plant and is an important medicinal plant from the Myrtaceae family that has been used for a long time in Indian and other traditional medicines across the world. Jamun is mainly cultivated in Asian countries such as Pakistan, India, Sri Lanka, and Bangladesh. Since ancient medicine, it has been utilized to treat a variety of diseases and physiological conditions. Currently, it is mostly used as a medication to treat various metabolic issues, including diabetes, hyperlipidemia, hypertension, obesity, etc. Therefore, Jamun could serve a beneficial role against metabolic syndrome (MS). In this work, the latest available scientific literature on Jamun was collected and the clinical trials investigating its effect on diabetes, hypertension, obesity, and hyperlipidemia were analyzed to find out how Jamun could improve the symptoms and biomarkers of MS. Overall, the results of this study found a significant association of Jamun with the prevention and treatment of these biomarkers of MS. In many studies, Jamun showed pharmacological modifications not only in MS but in many other diseases as well. Currently, its utilization as a folk medicine for the treatment of patients with MS is widely acknowledged. Hence, the findings of a large number of clinical studies confirmed the ameliorating effects of Jamun against MS due to its antioxidation, antidiabetic, anti-inflammation anticarcinogenic, and hyperlipidemic effects. More research is still needed to determine and identify the Jamun compounds and to elucidate their mechanisms of action that are responsible for these astounding bioactive properties and health benefits.