Evaluation of different therapeutic approaches for spontaneous bacterial peritonitis

Elaal, Mohammad M. Abd; Zaghloul, Sahar Gouda; Bakr, Hoda Gouda; Ashour, Mahmmoud Abdou; Abdel-Aziz-El-Hady, Hoda; Khalifa, Naglaa Ali; Amr, Ghada E.

doi:10.1016/j.ajg.2012.06.003

Cited by 4 publications

(1 citation statement)

References 37 publications

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“…For patients with cirrhotic ascites accompanied by SBP, 1.5 g/kg HSA is administered on Day 1 and then 1 g/kg on days 2-5. There was a marked decline in the incidence of renal failure, mortality during hospitalization, and 3-month mortality in patients with cirrhosis who received HSA compared with those who did not (4.7, 3.1, and 7% compared with 25.6, 38.2, and 47%, respectively) [44]. In recently ANSWER study, long-term HA (40 g twice weekly for 2 weeks, and then 40 g weekly for up to 18 months) administration prolongs overall survival and might act as a disease modifying treatment in patients with decompensated cirrhosis [45].…”

Section: Nutritional Support and Sodium Restrictionmentioning

confidence: 97%

Chinese guidelines on the management of ascites and its related complications in cirrhosis

Duan

Ding

et al. 2019

Hepatol Int

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The Chinese Society of Hepatology developed the current guidelines for the Management of Ascites and Its Related Complications in Cirrhosis based on the published evidences and the panelists' consensus. The guidelines provided recommendations for the diagnosis and management of cirrhotic ascites emphasizing a step-wise approach with the first-, second-, and thirdline therapy. For refractory ascites, vasoconstrictors and albumin are recommended for splanchnic vasodilation and selective vasopressin (V2) receptor antagonists for moderate-to-severe hyponatremia. For spontaneous bacterial peritonitis, empirical anti-infection treatment was recommended based on the local microbiological examination of community-or hospitalacquired infections. For hepatorenal syndrome, the administration of vasopressor terlipressin and albumin is recommended.

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Section: Nutritional Support and Sodium Restrictionmentioning

confidence: 97%