Abstract:Background and purposes:Tuberculosis (TB) is the most lethal infectious disease worldwide. About 24.6% of tuberculosis cases are extrapulmonary TB which commonly affects spine. Spinal tuberculosis (STB) is difficult to diagnose. This study aims to evaluate the diagnostic performance of MGIT-960 culture, T-SPOT.TB, Xpert MTB/RIF, and Metagenomic Next-Generation Sequencing (mNGS) in detecting STB.
Methods:
126 patients presumed to have STB were tested by 4 methods. Sensitivity, specificity, positive predictive v… Show more
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