Evaluation of cytotoxicity and antiviral activity of Rhazya stricta Decne leaves extract against influenza A/PR/8/34 (H1N1)

Albeshri, Abdulaziz; Baeshen, Nabih A.; Bouback, Thamer A.; Aljaddawi, Abdullah A.

doi:10.1016/j.sjbs.2022.103375

Cited by 5 publications

(1 citation statement)

References 31 publications

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“…Bovine serum albumin (BSA) was used as a standard. DNA was extracted as Baeshin, Qari, and Sabir (2007) DNA solutions were evaluated at 260 and 280nm by UV Spectrophotometer (V2.1.4).…”

Section: Methodsmentioning

confidence: 99%

Bioactivity and biochemical efficacy of chitinase and Justicia brandegeana extract against Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae)

Shehawy

Ibrahim

Aboutaleb

et al. 2020

Food Science & Nutrition

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The red palm weevil Rhynchophorus ferrugineus is a large polyphagous insect, and this study was carried out to isolate chitinase from Beauveria bassiana as well as phytochemical screening of Justicia brandegeana to elucidate its effect as biocontrol agents against the red palm weevil and its possible effect on enzymatic bioactivity. It is the first time that the lipoid constituents of J. brandegeana were examined by both gas–liquid chromatography (GLC) and gas chromatography–mass spectrometry (GC/Mass). The results showed that the highest rates of mortality in treated prepupae were 35.0% and 30.0% with the higher concentration of chitinase (25 ppm) and petroleum ether extract of J. brandegeana (1,200 ppm), respectively. Moreover, changes in enzyme activity of ALP, PO, GPT, and GOT in the prepupal stage after treatment with LC50 chitinase and J. brandegeana extract were 36.63 & 14.32, −21.99 & 41.20, −11.02 & 47.05, and −36.00 & 21.43% compared with untreated control, respectively. This study demonstrated effectiveness of chitinase, and the petroleum ether extract of J. brandegeana has potent effect against Rh. ferrugineus due to its disturbance effect on the enzymatic system, protein as well as DNA damage.

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“…Bovine serum albumin (BSA) was used as a standard. DNA was extracted as Baeshin, Qari, and Sabir (2007) DNA solutions were evaluated at 260 and 280nm by UV Spectrophotometer (V2.1.4).…”

Section: Methodsmentioning

confidence: 99%

Bioactivity and biochemical efficacy of chitinase and Justicia brandegeana extract against Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae)

Shehawy

Ibrahim

Aboutaleb

et al. 2020

Food Science & Nutrition

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Antiviral Significance of Isoquercetin (Quercetin-3-O-Glucoside) With Special Reference to its Anti-Coronaviral Potential

Agrawal,

Blunden,

Jacob

2024

Natural Product Communications

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Isoquercetin, a naturally occurring dietary flavonoid glycoside, has shown many promising biological activities, such as antioxidant, anti-inflammatory, and anticancer. It also exhibits broad-spectrum antiviral activity, significantly reducing cell infection by influenza, Zika, Ebola, and dengue viruses, among others. Its beneficial effect for mitigating the disease of COVID-19 can be explained due to its inhibitory effects on several stages of the viral life cycle, from entry to replication and virus infectivity, and thus isoquercetin can be a promising anticoronaviral flavonoid to manage severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection and warrants further investigation into its potential use in clinical settings.

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Skin- and Eco-Friendly Hand Sanitizer: A Novel Composition of Natural Extracts to Prevent the Spread of Respiratory Viruses

Gomes,

Zuchi,

Pavi

et al. 2024

AAPS PharmSciTech

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Evaluation of cytotoxicity and antiviral activity of Rhazya stricta Decne leaves extract against influenza A/PR/8/34 (H1N1)

Cited by 5 publications

References 31 publications

Bioactivity and biochemical efficacy of chitinase and Justicia brandegeana extract against Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae)

Bioactivity and biochemical efficacy of chitinase and Justicia brandegeana extract against Red Palm Weevil Rhynchophorus ferrugineus Olivier (Coleoptera: Curculionidae)

Antiviral Significance of Isoquercetin (Quercetin-3-O-Glucoside) With Special Reference to its Anti-Coronaviral Potential

Skin- and Eco-Friendly Hand Sanitizer: A Novel Composition of Natural Extracts to Prevent the Spread of Respiratory Viruses

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