Evaluation of creatine kinase (CK) and aspartate aminotransferase (AST) activities after laparoscopic or conventional ovariectomy in queens

Abstract

Creatine kinase (CK) and aspartate aminotransferase (AST) are mainly muscle-specific enzymes, which can be associated with muscle tissue damage. The aim of this study was to assess the activities of CK and AST during the postoperative period, after conventional (G1) and videolaparoscopic ovariectomy (G2), in queens. A further group (G3) was subjected to anaesthesia only. Results demonstrate that there were significant differences between groups. The highest levels of CK were recorded in G1, however at a confidence level of p<0.05 there was no significant difference between groups during the first 6 hours after surgery. A significant (p<0.05) increase of CK values was identified between 0 h and 3 h in both groups (G1 and G2). Regarding AST activity there was no significant variation between groups, but again there was a significant difference between values at 0 h and 3h after surgery. In conclusion, ovariectomy performed by videolaparoscopy seems to cause less muscle damage when compared to the conventional method.

Comparison of Surgical Variables and Pain in Cats Undergoing Ovariohysterectomy, Laparoscopic-Assisted Ovariohysterectomy, and Laparoscopic Ovariectomy

“…6,8,9,13 The severity of pain is likely related to the degree of soft-tissue trauma, pH of the peritoneal fluid, duration of the surgical procedure, and phrenic nerve irritation. 5,6,8,9,[15][16][17][18] In veterinary medicine, there has been increasing interest in performing minimally invasive surgery in cats. The proposed benefits are similar to those reported in dogs; however, the small size of the patient may make laparoscopic surgery more difficult and time consuming, which could be detrimental to the patient and increase morbidity.…”

Systemic effects of periodontal disease in cats

“…Aside from primary hepatocellular disease in cats, elevated AST activity is seen in diverse responses including muscle injury from ovariohysterectomy, Feline leukemia virus infection, anorexia, distal aortic thromboembolism, and hyperthyroidism (Laste and Harpster 1995;Broussard et al 1995;Fascetti et al 1997;Alves et al 2009;Gleich and Hartmann 2009). AST is found in a wide range of feline tissues, although hepatic and muscle sources are thought to be the only sources large enough to lead to elevated serum concentrations.…”

Evaluation of a laparoscopically assisted ovariectomy technique in cats

“…Studies comparing laparoscopic with open techniques for neutering female dogs and cats have shown less postoperative pain with laparoscopic techniques . One study showed a lower indication of muscle damage when performing laparoscopic ovariectomy compared with open ovariectomy . Potential advantages of laparoscopy include good visualization, lower risk of hemorrhage, faster recovery, and lower risk of infection .…”

“…3,[6][7][8][9] One study showed a lower indication of muscle damage when performing laparoscopic ovariectomy compared with open ovariectomy. 10 Potential advantages of laparoscopy include good visualization, 3,9,11 lower risk of hemorrhage, 6 faster recovery, 6,9 and lower risk of infection. 11 Disadvantages include the learning curve required for proficient use and the cost of the equipment.…”