Evaluation of Corneal Biomechanical Properties in Patients With Thyroid Eye Disease Using An Ocular Response Analyzer

Yüksel, Nilay; Kars, Meltem Ece

doi:10.1097/ijg.0000000000000476

Cited by 4 publications

(2 citation statements)

References 9 publications

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“…In the active phase, the increased inflammatory cytokine may affect the ocular biomechanical response parameters and result in a more pronounced increase in IOP. 46 Therefore, the subgroup analysis is necessary to clarify the characteristics in patients with active and inactive TED. 46 Future studies could investigate the corneal biomechanical response parameters in patients with active TED.…”

Section: Discussionmentioning

confidence: 99%

“… 46 Therefore, the subgroup analysis is necessary to clarify the characteristics in patients with active and inactive TED. 46 Future studies could investigate the corneal biomechanical response parameters in patients with active TED. Second, there was only one preoperative and one postoperative measurement with the Corvis ST, which may limit the reliability of the findings.…”

Section: Discussionmentioning

confidence: 99%

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The Changes in Ocular Biomechanical Response Parameters and Intraocular Pressure After Surgical Treatment for Thyroid Eye Disease

Hsia

Wei

Liao

2023

Invest. Ophthalmol. Vis. Sci.

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Purpose To investigate changes in ocular biomechanical response parameters and intraocular pressure (IOP) in patients with thyroid eye disease (TED) undergoing orbital decompression or anterior blepharotomy. Methods Eighty-three eyes from 46 patients receiving orbital decompression (the orbital decompression group) and 45 eyes from 28 patients receiving anterior blepharotomy (the anterior blepharotomy group) were retrospectively enrolled from a tertiary center. Corvis ST tonometry was used to assess ocular biomechanical response and biomechanically corrected IOP (bIOP) pre- and postoperatively. Non-contact tonometry (IOP-NCT) was also performed. Results In the anterior blepharotomy group, the margin reflex distance decreased ( P < 0001). The highest concavity radius ( P = 0.026) and whole eye movement ( P = 0.003) increased. Neither IOP-NCT nor bIOP had a significant change. In the orbital decompression group, the extent of exophthalmos decreased ( P < 0.001). The A2 length ( P = 0.009) decreased. The bIOP did not show a significant change (16.4 ± 2.7 vs. 16.7 ± 4.5; P = 0.415), but the IOP-NCT decreased significantly (17.5 ± 3.3 vs. 16.0 ± 3.3; P < 0.001). Higher baseline IOP-NCT (β = −0.40, P < 0.001) and greater reduction in stiffness parameter A1 (SP-A1; β = 0.05, P = 0.002) were associated with more significant IOP-NCT reduction after the orbital decompression. Conclusions Ocular biomechanical response parameters may change after TED surgery, potentially affecting IOP measurements, particularly in patients receiving orbital decompression.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%