Evaluation of Corneal Biomechanical Properties in Patients with Rheumatoid Arthritis: A Study by Ocular Response Analyzer

Abstract

RA patients had lower CH and CRF, but higher IOPcc values than healthy controls. RA should be considered when the corneal biomechanical properties measured by the ORA are used for diagnoses or therapies.

The Effect of Duration of Disease on Corneal Biomechanical Properties in Patients with Rheumatoid Arthritis

“…These findings are unlikely to those previous studies reported by Prata et al, Tas et al and Can et al found RA patients have higher IOPcc measurements when compared to control group. 10,11,13 There may be an association between autoimmunity and glaucoma but we did not find increased IOP in RA patients in our study. Large groups are necessary to evaluate whether RA patients have higher IOP measurements according to their age with considering their systemic therapy.…”

“…A more comprehensive study has been reported by Tas et al with 39 patients with RA in which duration of disease was not mentioned. 11 They also found lower CH and CRF and higher IOPcc values than control group. In their study 2 of the patients had a history of corneal involvement and 5 had episcleritis.…”

“…CCT was reported as decreased in RA in previous studies reported by Villani et al, Prata et al and Tas et al Can et al found no difference between RA patients and control group similar to our study. 9,10,11,13 In our study dry eye tests were not taken into consideration when comparing groups so we do not know how many patients have dry eye which may affect CCT as some studies show lower CCT in dry eye patients. 25,26 One of the limitations of this study is that the systemic therapy of patients are unknown.…”

“…There are very few studies evaluating corneal biomechanical properties in patients with rheumatoid diseases. [10][11][12][13] In this study we compared corneal biomechanical properties of the patients with RA with healthy control subjects. Besides that, a comparison is made after RA patients categorized into two groups according to the duration of disease.…”

A Comparison of Corneal Biomechanical Properties in Patients With Psoriasis and Healthy Subjects

“…Taş et al 22 reported lower CH and CRF values in patients with rheumatoid arthritis compared with age-matched controls, and the authors found higher IOPg and IOPcc values compared with the control group. Taş et al 22 reported lower CH and CRF values in patients with rheumatoid arthritis compared with age-matched controls, and the authors found higher IOPg and IOPcc values compared with the control group.…”