Evaluation of Commercial Connectors for Active Neural Implants

Lancashire, Henry T.; Habibollahi, Maryam; Jiang, Dai; Demosthenous, Andreas

doi:10.1109/ner49283.2021.9441072

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Furthermore, encapsulation can be time-consuming and complex, hindering widespread adoption. The use of commercially available encapsulation materials is characterized by complex encapsulation processes, such as mixing or drying [ 44 , 45 , 46 ]. Uniform film-type encapsulation with a waterproofing effect and self-bonding properties that can be easily applied to resolve these problems is required.…”

Section: Introductionmentioning

confidence: 99%

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

Lyu

Seong

et al. 2023

Polymers

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Polymers for implantable devices are desirable for biomedical engineering applications. This study introduces a water-resistant, self-healing fluoroelastomer (SHFE) as an encapsulation material for antennas. The SHFE exhibits a tissue-like modulus (approximately 0.4 MPa), stretchability (at least 450%, even after self-healing in an underwater environment), self-healability, and water resistance (WVTR result: 17.8610 g m−2 day−1). Further, the SHFE is self-healing in underwater environments via dipole–dipole interactions, such that devices can be protected from the penetration of biofluids and withstand external damage. With the combination of the SHFE and antennas designed to operate inside the body, we fabricated implantable, wireless antennas that can transmit information from inside the body to a reader coil that is outside. For antennas designed considering the dielectric constant, the uniformity of the encapsulation layer is crucial. A uniform and homogeneous interface is formed by simply overlapping two films. This study demonstrated the possibility of wireless communication in vivo through experiments on rodents for 4 weeks, maintaining the maximum communication distance (15 mm) without chemical or physical deformation in the SHFE layer. This study illustrates the applicability of fluoroelastomers in vivo and is expected to contribute to realizing the stable operation of high-performance implantable devices.

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Section: Introductionmentioning

confidence: 99%

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

Lyu

Seong

et al. 2023

Polymers

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Initial Life Test of Silicone Encapsulated FR4 Printed Circuit Boards for Pre-Clinical Active Implants

Ali,

Xue,

Henriquez

et al. 2023

2023 24th European Microelectronics and Packaging Conference &Amp; Exhibition (EMPC)

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Silicone encapsulated FR4 printed circuit boards may provide a rapid solution for protecting pre-clinical prototype implant electronics. Interdigitated electrodes (IDEs) with and without solder coating were manufactured on Cu-FR4 laminates and silicone encapsulated (N = 14). IDEs were aged in saline and change in impedance was measured. Solder coated IDEs had stable 1 kHz impedances throughout the aging period with promising lifetimes for pre-clinical prototypes. A single uncoated IDE failed with a fall in impedance and verdigris. Other uncoated IDEs showed increasing impedance and dark copper(II) oxide. Failures attributable to contaminants and moisture ingress are under investigation.

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Evaluation of Commercial Connectors for Active Neural Implants

Cited by 2 publications

References 13 publications

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

A Water-Resistant, Self-Healing Encapsulation Layer for a Stable, Implantable Wireless Antenna

Initial Life Test of Silicone Encapsulated FR4 Printed Circuit Boards for Pre-Clinical Active Implants

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