Evaluation of clinical spectrum and risk factors in young stroke patients at a tertiary level hospital, Patna, Bihar

Abstract

Background: Stroke is the most frequent neurological disorder that results in long-term disability and has significant emotional and socioeconomic effects for patients, their families, and health-care providers. The strongest link between patient and the risk of stroke is age. The age-specific incidence of stroke rises steadily as people get older. Aim: To evaluate clinical spectrum and risk factors in young stroke patients and to study epidemiology and etiology of young stroke patients at a tertiary level hospital, Patna, Bihar.Methods and Materials: Detailed clinical history was taken. Patients were clinically evaluated Laboratory investigations parameters included CBC, RFT, LFT, APTT, PT, VDRL, Lipid profile, FBS, PPBS, HbA1C, viral marker. Autoimmune profile-ANA, APLA profile, vasculitis marker. CXR, ECG, 2D Echo, 24 hr holter. Neuromaging was carried out with the help of NCCT MRI MRA. Results: When there was analysis of prevalence of risk factors in the young stroke patients then the most prevalent risk factors were atherosclerotic changes. However there were other risk factors found in stroke patients like rheumatic heart disease, vasculopathies and connective tissue disorders like SLE. Mitochondrial disorders, genetic disorders, post tubercular infarcts, traumatic heart diseases, chronic and acute disorders of head and neck, risk factors related to postpartum. etc.