Evaluation of chronic idiopathic tinnitus and its psychosocial triggers

Hamed, Sherifa A.; Attiah, Fadia Ahmed; Fawzy, Mohamed; Azzam, Mohamed

doi:10.12998/wjcc.v11.i14.3211

Cited by 2 publications

(2 citation statements)

References 37 publications

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“…[ 1 ] Idiopathic tinnitus is also called neurological tinnitus with or without hearing loss. [ 2 ] It is a subjective feeling that the patient consciously has a sound in the ear or intracranial, but there is no corresponding sound source outside. [ 3 ] Tinnitus is easy to cause anxiety and depression in patients, which seriously affects their quality of life.…”

Section: Introductionmentioning

confidence: 99%

Investigating acupoint selection and combinations of acupuncture for primary idiopathic tinnitus using data mining

Huang,

Fan,

Lin

et al. 2024

Medicine

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Background: Acupuncture is widely used in the treatment of tinnitus worldwide because of its good efficacy and safety. However, the criteria for selecting acupoint prescriptions and combinations have not been summarized. Therefore, data mining was used herein to determine the treatment principles and the most effective acupoint selection for the treatment of idiopathic tinnitus. Methods: The clinical research literature of acupuncture in the treatment of idiopathic tinnitus from the establishment of the database to September 1, 2023 in China National Knowledge Infrastructure, China Medical Journal Full-text Database, PubMed, Embase, Cochrane Library and Web of Science databases was retrieved and extracted. Microsoft Excel 2016 was used to establish the acupoint prescription database and the frequency statistics of acupoints, meridians and specific acupoints were carried out. IBM SPSS Statistics 25.0 software was used for cluster analysis of acupoints, and IBM SPSS Modeler18.0 software was used for association rule analysis of acupoints. Results: A total of 112 articles were included, involving 221 acupuncture prescriptions, including 99 acupoints, with a total frequency of 1786 times. The 5 most frequently used acupoints were Tinggong (SI19), Tinghui (GB2), Yifeng (TE17), Ermen (TE21), and Zhongzhu (TE3). The commonly used meridians were Sanjiao meridian of hand-shaoyang, Gallbladder meridian of foot-shaoyang and Small intestine meridian of hand-taiyang. The specific points are mostly Crossing point, Five-shu point and Yuan-primary point. The core acupoint combination of association rules was Ermen (TE21)–Tinggong (SI19)–Tinghui (GB2)–Yifeng (TE17), and 3 effective clustering groups were obtained by cluster analysis of high-frequency acupoints. Conclusion: In this study, the published literature on acupuncture treatment of idiopathic tinnitus was analyzed by data mining, and the relationship between acupoints was explored, which provided a more wise choice for clinical acupuncture treatment of idiopathic tinnitus.

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Section: Introductionmentioning

confidence: 99%

Investigating acupoint selection and combinations of acupuncture for primary idiopathic tinnitus using data mining

Huang,

Fan,

Lin

et al. 2024

Medicine

View full text Add to dashboard Cite

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“…Elucidating these could help to uncover the factors of hearing loss that contribute to tinnitus and suggest treatment options. In humans, differential susceptibility to tinnitus appears to be related to the severity of neuropsychiatric characteristics such as symptoms of depression, anxiety, stress or cognitive impairment (Trevis et al, 2018;Bhatt et al, 2022;Hamed et al, 2023). Research on tinnitus susceptibility using animal models, consistently showing that noise exposure leads to behavioral manifestations of phantom perception in only half of the subjects tested (Li et al, 2015;Mohrle et al, 2019;Fabrizio-Stover et al, 2022), then further suggested cellular and molecular mechanisms of resistance to tinnitus induction.…”

Section: Introductionmentioning

confidence: 99%

Mice prone to tinnitus after acoustic trauma show increased pre-exposure sensitivity to background noise

Rybalko,

Suchánková,

Bureš

et al. 2023

Front. Behav. Neurosci.

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Noise-induced tinnitus is generally associated with hearing impairment caused by traumatic acoustic overexposure. Previous studies in laboratory animals and human subjects, however, have observed differences in tinnitus susceptibility, even among individuals with similar hearing loss. The mechanisms underlying increased sensitivity or, conversely, resistance to tinnitus are still incompletely understood. Here, we used behavioral tests and ABR audiometry to compare the sound-evoked responses of mice that differed in the presence of noise-induced tinnitus. The aim was to find a specific pre-exposure neurophysiological marker that would predict the development of tinnitus after acoustic trauma. Noise-exposed mice were screened for tinnitus-like behavior with the GPIAS paradigm and subsequently divided into tinnitus (+T) and non-tinnitus (−T) groups. Both groups showed hearing loss after exposure, manifested by elevated audiometric thresholds along with reduced amplitudes and prolonged latencies of ABR waves. Prior to exposure, except for a slightly increased slope of growth function for ABR amplitudes in +T mice, the two groups did not show significant audiometric differences. Behavioral measures, such as the magnitude of the acoustic startle response and its inhibition by gap pre-pulse, were also similar before exposure in both groups. However, +T mice showed significantly increased suppression of the acoustic startle response in the presence of background noise of moderate intensity. Thus, increased modulation of startle by background sounds may represent a behavioral correlate of susceptibility to noise-induced tinnitus, and its measurement may form the basis of a simple non-invasive method for predicting tinnitus development in laboratory rodents.

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Evaluation of chronic idiopathic tinnitus and its psychosocial triggers

Cited by 2 publications

References 37 publications

Investigating acupoint selection and combinations of acupuncture for primary idiopathic tinnitus using data mining

Investigating acupoint selection and combinations of acupuncture for primary idiopathic tinnitus using data mining

Mice prone to tinnitus after acoustic trauma show increased pre-exposure sensitivity to background noise

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