Evaluation of children with ventricular arrhythmias.

Radford, Dorothy J.; Izukawa, T; Rowe, Richard D.

doi:10.1136/adc.52.5.345

Cited by 24 publications

(9 citation statements)

References 32 publications

(29 reference statements)

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“…Of the 18 patients in whom programmed stimulation was performed, 11 (61%) had inducible sustained ventricular tachycardia with a QRS morphology that was identical to their clinical tachycardia. In two additional patients, nonsustained tachycardia identical to their clinical exer- Overall mortality in this population was 13% (3/24 patients).…”

Section: Resultsmentioning

confidence: 99%

Ventricular tachycardia in a young population without overt heart disease.

Deal¹,

Miller²,

Scagliotti³

et al. 1986

Circulation

167

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Since 1974, 24 young patients presenting with ventricular tachycardia and without clinical evidence of heart disease were evaluated and followed. Sixteen patients (67%) were symptomatic. Clinical episodes of ventricular tachycardia were sustained in 18, incessant in four, and nonsustained in two patients. The rate of tachycardia ranged from 130 to 300 beats/min (mean = 200 beats/min). Subtle abnormalities of cardiac size or function were present at cardiac catheterization in 16 of 23 patients (70%). During electrophysiologic studies, spontaneous ventricular tachycardia was present in six patients. The clinical ventricular tachycardia was inducible by programmed stimulation in 13 of 18 patients. The site of origin of tachycardia based on endocardial mapping in 17 patients was the right ventricle in 14, the ventricular septum in one, and indeterminate in two patients. Seventeen patients were treated based on results of short-term drug testing. During a mean follow-up period of 7.5 years, three patients died suddenly; none of these patients were receiving antiarrhythmic medication at the time of death. We conclude that in a young population without clinical evidence of heart disease, ventricular tachycardia may be the first manifestation of cardiomyopathy, since at least two-thirds of these patients have abnormalities at cardiac catheterization. Without treatment mortality in this population may be as high as 13% over an 8 year period. Presently we recommend treatment of ventricular tachycardia in any symptomatic patient, with therapy guided by electrophysiologic and treadmill testing. In addition, we recommend treatment for any asymptomatic patient with exercise-related tachycardia, since this group appears to be at increased risk for sudden death. Finally, we would seriously consider treating any asymptomatic patient in whom sustained monomorphic ventricular tachycardia can be induced by standard programmed stimulation protocols, although the long-term prognosis in this group is uncertain.

show abstract

Section: Resultsmentioning

confidence: 99%

Ventricular tachycardia in a young population without overt heart disease.

Deal¹,

Miller²,

Scagliotti³

et al. 1986

Circulation

167

View full text Add to dashboard Cite

show abstract

“…Radford and Izukawa noted that atrial fibrillation in childhood may occur at any age, with nearly 50% of those reported by presenting after age 10 years (Radford & Izukawa, 1977). In describing the children with this arrhythmia, they described four cases of atrial fibrillation associated with supraventricular tachycardia (without structural heart disease) and one case of "lone" atrial fibrillation (Radford & Izukawa, 1977).…”

Section: Atrial Fibrillation In Children Without Structural Heart Dismentioning

confidence: 99%

“…In describing the children with this arrhythmia, they described four cases of atrial fibrillation associated with supraventricular tachycardia (without structural heart disease) and one case of "lone" atrial fibrillation (Radford & Izukawa, 1977). Atrial fibrillation in the absence of structural heart disease, or "lone" atrial fibrillation, accounted for 6% of the older children in this series.…”

Section: Atrial Fibrillation In Children Without Structural Heart Dismentioning

confidence: 99%

“…The seminal report of Radford and Izukawa on atrial fibrillation in children examined the spectrum of conditions associated with this arrhythmia (Radford & Izukawa, 1977). In the 35 cases of atrial fibrillation in children reported, associated conditions included rheumatic heart disease, cardiomyopathy, atrial tumors, infective endocarditis, Marfan syndrome, endocardial fibroelastosis and structural congenital heart disease (Radford & Izukawa, 1977).…”

Section: Atrial Fibrillation In Children With Myocarditis Cardiomyopmentioning

confidence: 99%

“…Benign tumors that arise in the pericardium may also cause mechanical pressure on the atria due to the limited space available to them to grow. All of these may lead to atrial fibrillation, and the resulting clinical impact (Chen et al, 1992;Cooper et al, 1994;Radford & Izukawa, 1977).…”

Section: Atrial Fibrillation In Children With Myocarditis Cardiomyopmentioning

confidence: 99%

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