Evaluation of Chest CT scan as a screening and diagnostic tool in trauma patients with coronavirus disease 2019 (COVID-19): a cross-sectional study in southern Iran

Fard, Hossein Abdolrahimzadeh; Mahmudi‐Azer, Salahaddin; Sefidbakht, Sepideh; Iranpour, Pooya; Bolandparvaz, Shahram; Abbasi, Hamid Reza; Paydar, Shahram; Sabetian, Golnar; Mahmoudi, Mohamad Mahdi; Zare, Masoume; Shayan, Leila; Salimi, Maryam

doi:10.21203/rs.3.rs-110402/v2

Cited by 6 publications

(5 citation statements)

References 12 publications

(12 reference statements)

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“…[22] During the treatment of COVID-19 and its complications, the use of corticosteroids caused a decrease in lung inflammation, cytokine storm, and fever. [23] [24] These studies however neither confirm that corticosteroids are the sole independent risk factor nor eliminate them as a risk factor. Diagnostic confirmation can be obtained by (a) direct microscopy with slides mounted with potassium hydroxide, particularly when it is necessary to start therapy immediately; (b) fungal culture; (c) biopsy of the affected lesions with adequate precaution; (d) radiological (computed tomography of osteomeatal complex and magnetic resonance imaging with contrast) examinations.…”

Section: The Physicianmentioning

confidence: 99%

COVID-19 Associated Mucormycosis

Francis,

Goel,

Gandhi

et al. 2023

phy

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This case series explores Covid-19 associated Mucormycosis (CAM), its risk factors, clinical features and outcomes from a tertiary centre in Maharashtra, India, during the second wave of COVID-19. Methods: A retrospective, observational case series of 104 consecutive patients admitted to the hospital at various stages of complications of CAM, during the second wave of the COVID-19 pandemic (Jan’21-Apr’21). The diagnosis was confirmed using Potassium hydroxide wet mount (KOH), histopathology, fungal culture, and Cone-Beam Computed Tomography(CBCT). Results: There were 81% men, mean age of 49 ± 12.4 years, and all patients had a history of corticosteroids usage, 82% had a prior diagnosis of diabetes mellitus (DM) and the rest were newly diagnosed. Diagnosis of mucormycosis was confirmed on 2 modalities in 71%; KOH and histopathology in 31 (30%), and fungal culture with KOH and histopathology together detected 25 (24%). 9% were diagnosed exclusively with CBCT. Patients with prior DM had higher morbidity OR 8.30 [95% CI: 2.12, 32.5; p=0.002] and mortality OR 13.23 [95% CI: 1.67, 104.7; p=0.014] than non-DM patients. Mortality was higher in patients with rhino + orbital involvement than patients with rhino + maxillary involvement [OR 8.37 [95% CI: 1.52, 46.09; p=0.014]. Conclusion: Diabetes remained the highest risk factor for the development of CAM in patients with COVID-19 on corticosteroids, with high mortality and morbidity. Timely medical and surgical interventions and multi-disciplinary approaches could potentially reduce mucormycosis-associated mortality. Among the diagnostic modalities, detection using CBCT may increase the diagnostic yield in patients not detected in other modalities.

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Section: The Physicianmentioning

confidence: 99%

COVID-19 Associated Mucormycosis

Francis,

Goel,

Gandhi

et al. 2023

phy

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“…Inclusion criteria were confirmed case of COVID-19, patients with available medical records, and those with informed consent. The COVID-19 diagnosis was confirmed by a positive SARS-CoV-2 RT-PCR using throat and nose swab from the upper respiratory tract sample or was clinically diagnosed based on lung imaging findings, especially chest CT scan ground glass pathognomonic features consistent with coronavirus pneumonia (31)(32)(33) when RT-PCR tests were not available. The admission criteria were as follows:…”

Section: Study Design and Participantsmentioning

confidence: 99%

Outcome, Severity, and Risk of Mortality in Patients with COVID-19 and Chronic Underlying Diseases: A Prospective Study

Salimi¹,

Aghaziarati²,

Balalami³

et al. 2022

Arch Clin Infect Dis

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Background: The novel coronavirus pandemic, severe acute respiratory syndrome CoV-2 (SARS COV-2), has become a global threat and rapidly spread worldwide. The COVID-19 pandemic has posed a number of challenges, the most notable of which is the management of patients with chronic underlying diseases. Objectives: The present study aimed to evaluate the risk of COVID-19 severity and mortality in patients with chronic underlying diseases. Methods: In this retrospective cohort study, the data on the disease severity and morality of confirmed COVID-19 patients admitted to Baharloo Hospital, Tehran, Iran, from February 2020 to March 2020 were analyzed and reported. Patients’ characteristics, including age, gender, and underlying diseases, were also considered. Results: The study encompassed 1244 patients with the mean age of 53.29 years, among whom there were 573 patients with at least one co-existing chronic disease. Hypertension, diabetes mellitus (DM), and ischemic heart disease (IHD) were the most common co-existing chronic diseases. The findings revealed that underlying diseases were significantly associated with disease mortality and severity. Conclusions: The findings showed that patients with comorbidities were significantly at higher risk of death and severe forms of COVID-19. In this regard, patients with underlying diseases should be of concern.

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“…For example, digital technologies can prevent digital isolation, boost connectivity, and provide access to tools and information, which can provide insightful information on populations to achieve health objectives. Digital health technologies have been at the forefront of the COVID-19 pandemic and have caused a shift toward telehealth (eg, virtual visits, care, and e-prescriptions), mobile apps (patient monitoring), and instant messaging applications (risk assessment and screening, triage, etc) [ 32 - 34 ].…”

Section: Digital Health and Sdgs To Mitigate Infodemicsmentioning

confidence: 99%

The Pandemic, Infodemic, and People’s Resilience in India: Viewpoint

Syed-Abdul¹,

Ramaswamy²,

Fernández-Luque³

et al. 2021

JMIR Public Health Surveill

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The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused widespread fear and stress. The pandemic has affected everyone, everywhere, and created systemic inequities, leaving no one behind. In India alone, more than 34,094,373 confirmed COVID-19 cases and 452,454 related deaths have been reported as of October 19, 2021. Around May 2021, the daily number of new COVID-19 cases crossed the 400,000 mark, seriously hampering the health care system. Despite the devastating situation, the public response was seen through their efforts to come forward with innovative ideas for potential ways to combat the pandemic, for instance, dealing with the shortage of oxygen cylinders and hospital bed availability. With increasing COVID-19 vaccination rates since September 2021, along with the diminishing number of daily new cases, the country is conducting preventive and preparatory measures for the third wave. In this article, we propose the pivotal role of public participation and digital solutions to re-establish our society and describe how Sustainable Development Goals (SDGs) can support eHealth initiatives and mitigate infodemics to tackle a postpandemic situation. This viewpoint reflects that the COVID-19 pandemic has featured a need to bring together research findings across disciplines, build greater coherence within the field, and be a driving force for multi-sectoral, cross-disciplinary collaboration. The article also highlights the various needs to develop digital solutions that can be applied to pandemic situations and be reprocessed to focus on other SDGs. Promoting the use of digital health care solutions to implement preventive measures can be enhanced by public empowerment and engagement. Wearable technologies can be efficiently used for remote monitoring or home-based care for patients with chronic conditions. Furthermore, the development and implementation of informational tools can aid the improvement of well-being and dissolve panic-ridden behaviors contributing toward infodemics. Thus, a call to action for an observatory of digital health initiatives on COVID-19 is required to share the main conclusions and lessons learned in terms of resilience, crisis mitigation, and preparedness.

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Evaluation of Chest CT scan as a screening and diagnostic tool in trauma patients with coronavirus disease 2019 (COVID-19): a cross-sectional study in southern Iran

Cited by 6 publications

References 12 publications

COVID-19 Associated Mucormycosis

COVID-19 Associated Mucormycosis

Outcome, Severity, and Risk of Mortality in Patients with COVID-19 and Chronic Underlying Diseases: A Prospective Study

The Pandemic, Infodemic, and People’s Resilience in India: Viewpoint

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