Evaluation of California Non-Comprehensive Death File Against National Death Index

Chen, Xi; Park, Rebekah; Hurtado, Cecilia; Gransar, Heidi; Tep, Brian; Miranda-Peats, Romalisa; SooHoo, Spencer L.; Rozanski, Alan; Berman, Daniel S.

doi:10.1016/j.dialog.2022.100015

Cited by 3 publications

(2 citation statements)

References 15 publications

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“…Mortality status was determined using internal hospital records, the Social Security Death Index, National Death Index, and the California Non-Comprehensive Death File [ 15 ].…”

Section: Methodsmentioning

confidence: 99%

Downward myocardial creep during stress PET imaging is inversely associated with mortality

Kuronuma,

Miller,

Wei

et al. 2024

Eur J Nucl Med Mol Imaging

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Purpose The myocardial creep is a phenomenon in which the heart moves from its original position during stress-dynamic PET myocardial perfusion imaging (MPI) that can confound myocardial blood flow measurements. Therefore, myocardial motion correction is important to obtain reliable myocardial flow quantification. However, the clinical importance of the magnitude of myocardial creep has not been explored. We aimed to explore the prognostic value of myocardial creep quantified by an automated motion correction algorithm beyond traditional PET-MPI imaging variables. Methods Consecutive patients undergoing regadenoson rest-stress [82Rb]Cl PET-MPI were included. A newly developed 3D motion correction algorithm quantified myocardial creep, the maximum motion at stress during the first pass (60 s), in each direction. All-cause mortality (ACM) served as the primary endpoint. Results A total of 4,276 patients (median age 71 years; 60% male) were analyzed, and 1,007 ACM events were documented during a 5-year median follow-up. Processing time for automatic motion correction was < 12 s per patient. Myocardial creep in the superior to inferior (downward) direction was greater than the other directions (median, 4.2 mm vs. 1.3–1.7 mm). Annual mortality rates adjusted for age and sex were reduced with a larger downward creep, with a 4.2-fold ratio between the first (0 mm motion) and 10th decile (11 mm motion) (mortality, 7.9% vs. 1.9%/year). Downward creep was associated with lower ACM after full adjustment for clinical and imaging parameters (adjusted hazard ratio, 0.93; 95%CI, 0.91–0.95; p < 0.001). Adding downward creep to the standard PET-MPI imaging model significantly improved ACM prediction (area under the receiver operating characteristics curve, 0.790 vs. 0.775; p < 0.001), but other directions did not (p > 0.5). Conclusions Downward myocardial creep during regadenoson stress carries additional information for the prediction of ACM beyond conventional flow and perfusion PET-MPI. This novel imaging biomarker is quantified automatically and rapidly from stress dynamic PET-MPI.

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“…Mortality status was determined using internal hospital records, the Social Security Death Index, National Death Index, and the California Non-Comprehensive Death File [ 15 ].…”

Section: Methodsmentioning

confidence: 99%

Downward myocardial creep during stress PET imaging is inversely associated with mortality

Kuronuma,

Miller,

Wei

et al. 2024

Eur J Nucl Med Mol Imaging

Self Cite

View full text Add to dashboard Cite

show abstract

“…The primary endpoint was all-cause mortality (ACM). ACM was determined using internal hospital records as well as the Social Security Death Index, National Death Index, and California Non-Comprehensive Death File, which has previously been shown to be a reliable source for obtaining mortality status in the state of California [ 18 ].…”

Section: Methodsmentioning

confidence: 99%

Incremental prognostic value of stress phase entropy over standard PET myocardial perfusion imaging variables

Kuronuma

Miller

Kriekinge

et al. 2023

Eur J Nucl Med Mol Imaging

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Purpose Phase analysis can assess left ventricular dyssynchrony. The independent prognostic value of phase variables over positron emission tomography myocardial perfusion imaging (PET-MPI) variables including myocardial flow reserve (MFR) has not been studied. The aim of this study was to explore the prognostic value of phase variables for predicting mortality over standard PET-MPI variables. Methods Consecutive patients who underwent pharmacological stress-rest 82Rb PET study were enrolled. All PET-MPI variables including phase variables (phase entropy, phase bandwidth, and phase standard deviation) were automatically obtained by QPET software (Cedars-Sinai, Los Angeles, CA). Cox proportional hazard analyses were used to assess associations with all-cause mortality (ACM). Results In a total of 3963 patients (median age 71 years; 57% male), 923 patients (23%) died during a median follow-up of 5 years. Annualized mortality rates increased with stress phase entropy, with a 4.6-fold difference between the lowest and highest decile groups of entropy (2.6 vs. 12.0%/year). Abnormal stress phase entropy (optimal cutoff value, 43.8%) stratified ACM risk in patients with normal and impaired MFR (both p < 0.001). Among three phase variables, only stress phase entropy was significantly associated with ACM after the adjustment of standard clinical and PET-MPI variables including MFR and stress-rest change of phase variables, whether modeled as binary variables (adjusted hazard ratio, 1.44 for abnormal entropy [> 43.8%]; 95%CI, 1.18–1.75; p < 0.001) or continuous variables (adjusted hazard ratio, 1.05 per 5% increase; 95%CI, 1.01–1.10; p = 0.030). The addition of stress phase entropy to the standard PET-MPI variables significantly improved the discriminatory power for ACM prediction (p < 0.001), but the other phase variables did not (p > 0.1). Conclusion Stress phase entropy is independently and incrementally associated with ACM beyond standard PET-MPI variables including MFR. Phase entropy can be obtained automatically and included in clinical reporting of PET-MPI studies to improve patient risk prediction.

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10-year experience of utilizing a stress-first SPECT myocardial perfusion imaging

Han,

Hyun,

Miller

et al. 2024

International Journal of Cardiology

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Evaluation of California Non-Comprehensive Death File Against National Death Index

Cited by 3 publications

References 15 publications

Downward myocardial creep during stress PET imaging is inversely associated with mortality

Downward myocardial creep during stress PET imaging is inversely associated with mortality

Incremental prognostic value of stress phase entropy over standard PET myocardial perfusion imaging variables

10-year experience of utilizing a stress-first SPECT myocardial perfusion imaging

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