Evaluation of brainstem auditory evoked potential in type 2 diabetes mellitus individuals

Auditory and Vestibular Functioning in Individuals with Type-2 Diabetes Mellitus: A Systematic Review

“…A significant delay in the absolute latency of waves I, II, III, IV and V and interpeak latencies (IPLs) of waves I-III, I-V and III-V was observed in DM2 individuals. 37 Other studies 38,39 with DM2 patients and healthy controls have reported a significant increase in the absolute latencies of waves I, III and V and IPLs of waves III-V and I-V. Kannan 40 also reported an increase in both absolute latencies (of waves III and V) and IPLs (of waves I-III, I-V and III-V) in DM2 individuals compared with healthy controls. Studies 41,42 reporting the effect of stimulus intensity on AEPs in DM2 revealed a significant increase in the absolute latencies of waves III and V and IPLs of waves I-III, III-V and I-V at 70 dBnHL and 80 dBnHL, whereas, at 90 dBnHL, the authors found a significant increase in the absolute latency of wave I compared with that of the other two intensities.…”

“…It can be inferred from the aforementioned findings, that DM2 can result in reduced conduction velocity in the auditory nerve that occurs secondary to diabetic neuropathy. Some authors [37][38][39][40] suggest that the prolongation of wave I could be due to a reduction in the time of peripheral transmission, and that the prolongation of waves III and V could be due to a reduction in the time of central transmission. This can be attributed to the neuronal degeneration that results from the oxidative stress and apoptosis of neurons in DM2.…”