Evaluation of bacterial safety approaches of platelet blood concentrates: bacterial screening and pathogen reduction
Mohammad Reza Rezvany,
Amin Moradi Hasan-Abad,
Ali Sobhani-Nasab
et al.
Abstract:This mini-review analyzed two approaches to screening bacterial contamination and utilizing pathogen reduction technology (PRT) for Platelet concentrates (PCs). While the culture-based method is still considered the gold standard for detecting bacterial contamination in PCs, efforts in the past two decades to minimize transfusion-transmitted bacterial infections (TTBIs) have been insufficient to eliminate this infectious threat. PRTs have emerged as a crucial tool to enhance safety and mitigate these risks. Th… Show more
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