Evaluation of Arterial Blood Flow Changes by Orbital Doppler in Chronic Obstructive Pulmonary Disease and Asthma

Abstract

We concluded that retrobulbar hemodynamics change in COPD and asthma is showing 1 of the systemic effects in these diseases.

The alterations of retinal vasculature detected on optical coherence tomography angiography associated with chronic obstructive pulmonary disease

“…Chronic hypoxia and hypercapnia in COPD patients may affect choroidal and retinal blood flow. There are color Doppler ultrasonography studies showing that retrobulbar hemodynamics was impaired, retrobulbar blood flow was reduced, and resistance to blood flow was increased in both retinal and choroidal circulation in COPD patients 22–24 . In parallel with these studies, our study's OCTA results indicated a significant decrease in VD values of SCP and DCP, optic disc, and peripapillary region, especially in the temporal side, and a significant widening in FAZ in the COPD group.…”

Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients

“…Moreover, the EDVs of the arteries did not differ significantly between patients with COPD and control group (Ozer et al 2006). Yakut et al (2015) observed similar findings in 37 patients with COPD, 37 patients with asthma and 41 healthy controls. Resistive index (RI) values of the CRA, temporal PCA and nasal PCA were significantly higher in patients with COPD compared to controls.…”

“…Yakut et al. () observed similar findings in 37 patients with COPD, 37 patients with asthma and 41 healthy controls. Resistive index (RI) values of the CRA, temporal PCA and nasal PCA were significantly higher in patients with COPD compared to controls.…”

“…In addition, PSV and EDV were significantly higher. No differences were found between patients with COPD and patients with asthma (Yakut et al 2015).…”

“…Changes in PSV, EDV and RI are associated with various vascular disorders, and have predictive value for coronary artery diseases (Tranquart et al 2003;Maruyoshi et al 2010). Three studies used colour Doppler ultrasonography with patients with COPD, showing an increased PSV, EDV, and RI values of the ophthalmic artery (OA), central retinal artery (CRA) and posterior ciliary artery (PCA) in patients with COPD compared to non-COPD control subjects (Ozer et al 2006;Celik et al 2014;Yakut et al 2015). Ozer et al (2006) determined RI, pulsatility index (PI), PSV and EDV in the OA, CRA and PCA in 45 male patients with COPD and 17 male controls.…”