Evaluation of Antitumor Activity of Xanthones Conjugated with Amino Acids
Flávia Barbosa,
Joana Araújo,
Virgínia M. F. Gonçalves
et al.
Abstract:Cancer is a complex disease characterized by several alterations, which confer, to the cells, the capacity to proliferate uncontrollably and to resist cellular death. Multiresistance to conventional chemotherapy drugs is often the cause of treatment failure; thus, the search for natural products or their derivatives with therapeutic action is essential. Chiral derivatives of xanthones (CDXs) have shown potential inhibitory activity against the growth of some human tumor cell lines. This work reports the screen… Show more
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