Evaluation of Antioxidant Properties of <i>Phaulopsis fascisepala</i> C.B.Cl. (Acanthaceae)

Adesegun, SA; Fajana, A.; Orabueze, Celestina I.; Coker, H. A. B.

doi:10.1093/ecam/nem098

Cited by 70 publications

(65 citation statements)

References 28 publications

(28 reference statements)

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“…IC 50 values (concentration of sample required to scavenge 50% free radical) were found to be the least in GA (0.110±0.014 mg/mL), followed by ButR (0.211±0.017 mg/mL), BHA (0.214±0.004 mg/mL), TA (0.214±0.019 mg/mL) and TR (0.225±0.002 mg/mL). EAR (0.611±0.072 mg/mL) and PolyR (0.816± 0.007 mg/mL) also showed good activity compared to AA (0.413±0.041 mg/mL).…”

Section: Dpph (Diphenyl-1-picrylhydrazyl) Free Radical Scavenging Assaymentioning

confidence: 96%

“…Ethanol was used for baseline correction. The free radical scavenging activity is usually expressed as percentage of DPPH inhibition but also by the antioxidant concentration required for 50% DPPH reduction (IC 50 ). Basically, a higher DPPH radical scavenging activity is associated with a lower IC 50 value.…”

Section: % Dpph Radical Scavenging = [(A 0 -A T )/A 0 ] X 100mentioning

confidence: 99%

“…IC 50 value was determined from plotted graph of scavenging activity against the different concentrations of Z. lotus roots extracts, AA, GA, TA and BHA. The scavenging activity was expressed by the percentage of DPPH reduction after 60 min of reaction.…”

Section: % Dpph Radical Scavenging = [(A 0 -A T )/A 0 ] X 100mentioning

confidence: 99%

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Study on the antioxidant activities of root extracts of Zizyphus lotus from the western region of Algeria

Ghalem¹,

Merghache²,

Belarbi³

2014

Phcog J.

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Objective: To find a new natural source of antioxidant, the phenolic contents and antioxidant activities of some secondary metabolites extracted from roots of Ziziphus lotus were evaluated. Methods: The total polyphenol contents were determined spectrophotometrically. Pyrrocatechol, catechin and cyanidin equivalents were used for these parameters. The antioxidant activities of the extracts were determined by several in vitro systems of assays, namely DPPH radical scavenging activity method, b-Carotene Bleaching assay (BCB), Ferric Reducing Antioxidant Power assay (FRAP) and Total Antioxidant capacity test (TAC). Results: The quantitative estimation showed that the roots of Z. lotus were rich in polyphenols (20.09 mg PE/g DW) and proanthocyannidins (1.56%) and they contained a small amount of flavonoids (0.02 mg CE/g DW). The most fractions exhibited high antioxidant activities, and some even showed higher potency than the standard synthetic antioxidants in some instances. In DPPH assay, all extracts had shown significant inhibition (58.535 -94.730% at 1 mg/mL). In addition, the IC 50 values ranged from 0.211 to 0.816 mg/mL, compared to 0.110, 0.214, 0.214 and 0.413 mg/mL for gallic acid, tannic acid, butylated-hydroxyanisol and ascorbic acid respectively. In (BCB) assay, the extracts showed strong inhibition (55.55 -100.00% at 1 mg/mL) and the IC 50 values ranging from 0.123 to 0.850 mg/mL compared to 0.433 mg/mL for gallic acid. A dose dependant curve was obtained for all extracts in the FRAP assay. However, the antioxidant potencies of ascorbic acid and extracts were comparable at low concentrations. The majority of extracts showed the highest value of antioxidant activity, based on TAC test (0.073 -0.398 mg ascorbic acid / mg extract). Conclusion: The results indicate that Z. lotus roots could be an important sources of natural antioxidants.

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Section: Dpph (Diphenyl-1-picrylhydrazyl) Free Radical Scavenging Assaymentioning

confidence: 96%

Section: % Dpph Radical Scavenging = [(A 0 -A T )/A 0 ] X 100mentioning

confidence: 99%

See 1 more Smart Citation

Study on the antioxidant activities of root extracts of Zizyphus lotus from the western region of Algeria

Ghalem¹,

Merghache²,

Belarbi³

2014

Phcog J.

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“…Water soluble antioxidant potentials are determined based on the traditional method in intake of plant extracts therapeutically. The IC 50 values of extracts were calculated for DPPH and NO inhibition assays to compare the antioxidant activities at different concentrations as described by many authors (Adesegun et al, 2009;Marwah et al, 2007).The results of three in vitro assays (DPPH, FRAP, NO) for antioxidant properties of the 10 plant extracts are given in Table 1.…”

Section: Total Antioxidant Activitiesmentioning

confidence: 99%

Phytochemical screening and <i>In vitro</i> antioxidant potentials of extracts of ten medicinal plants used for the treatment of diabetes mellitus in Sri Lanka

Attanayake¹,

Jayatilaka²,

Pathirana³

et al. 2015

Afr. J. Trad. Compl. Alt. Med.

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Background: Over the last decade, extensive research work has focused on the potential health benefits of antioxidants while many medicinal plant extracts have been evaluated for their antioxidant profile. Medicinal plants selected for this study are widely used in traditional medicine for the treatment of diabetes mellitus in Sri Lanka some of which are recommended as dietary supplements to the existing therapies. The present study aimed at determining the total polyphenol contents and total antioxidant activities of aqueous extracts of 10 selected Sri Lankan medicinal plants by three in vitro methods; Materials and Methods: DPPH(2, 2-diphenyl-2-picrylhydrazyl), FRAP (ferric reducing power) and NO (nitric oxide) assays. The aqueous plant extracts were tested at the concentration of 0.05 g/mL. The total polyphenol content was determined according to the Folin-Ciocalteu method while the total antioxidant activity was evaluated by DPPH, FRAP and NO assays with L-ascorbic acid as reference compound. Results:The total polyphenol content of the plant extracts varied from 0.41 to 13.00 mg GAE (gallic acid equivalents) per gram dry weight. The antioxidant activities ranged in IC 50 of 36.89-101.27 µg/mL, IC 50 of 139.56-419.93 µg/mL, 0.12-8.98 µM for DPPH, NO, FRAP assays, respectively. A significant positive correlation was observed between total polyphenol content and antioxidant activities (P< 0.05). Conclusion: Phytochemical analysis revealed the presence of polyphenolic compounds, alkaloids and flavonoids in the plant materials which also possessed in vitro antioxidant potentials. Polyphenolic compounds contribute significantly to the total antioxidant capacities of medicinal plant extracts.

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“…It is also used as chewing stick for oral and dental healthcare (Kayode and Omotoyinbo, 2008). Another species, P. fascicepala, has been reported to possess antioxidant activity (Adesegun et al, 2009). …”

Section: Introductionmentioning

confidence: 99%

Terpenoids from Phaulopsis imbricata (Acanthaceae)

Kengne¹,

Téné²,

Tchinda³

et al. 2016

J. Med. Plants Res.

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The whole plant of Phaulopsis imbricata (Forssk.) Sweet (Acanthaceae) was collected at Bansoa, Cameroon, shade dried and extracted by maceration in methanol. This study was carried out to isolate secondary metabolites from this plant species that has not been investigated so far. Two lupane-type triterpenoids, one β-type carotenoid, one eudesmane-type sesquiterpenoid, and one sterol glycoside were isolated from the dried methanol extract using solvent partitioning, column chromatography and re-crystallization. They were identified as lupeol, betulin, (all-E)-lutein, cryptomeridiol, and sitosterol 3-O-β-D-glucopyranoside, respectively. The structures of the isolated compounds were elucidated on the basis of spectroscopic methods including 1D-and 2D-nuclear magnetic resonance (NMR), infrared (IR) and mass spectrometry (MS). This is the first report of these compounds from the genus Phaulopsis. To the best of our knowledge, P. imbricata is also the first species of the genus to be phytochemically studied.

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Evaluation of Antioxidant Properties of Phaulopsis fascisepala C.B.Cl. (Acanthaceae)

Cited by 70 publications

References 28 publications

Study on the antioxidant activities of root extracts of Zizyphus lotus from the western region of Algeria

Study on the antioxidant activities of root extracts of Zizyphus lotus from the western region of Algeria

Phytochemical screening and <i>In vitro</i> antioxidant potentials of extracts of ten medicinal plants used for the treatment of diabetes mellitus in Sri Lanka

Terpenoids from Phaulopsis imbricata (Acanthaceae)

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