Evaluation of antioxidant, antibacterial, and antidiabetic potential of two traditional medicinal plants of India: Swertia cordata and Swertia chirayita

Abstract

Background:Swertia cordata and Swertia chirayita are temperate Himalayan medicinal plants used as potent herbal drugs in Indian traditional systems of medicine (Ayurvedic, Unani and Siddha).Objective:Assessment of Antioxidant, antibacterial, and antidiabetic potential of Swertia cordata and Swertia chirayita.Materials and Methods:Phytochemicals of methanolic and aqueous extracts of the two Swertia species were analyzed. The antioxidant potential of all the extracts was assessed by measuring total phenolic content, total flavonoid content and free radical scavenging potential was assessed by 1,1-diphenyl-2-picrilhydrazyl (DPPH) assay, antibacterial activity was assessed against various pathogenic and nonpathogenic bacteria in vitro by Kirby-Bauer agar well diffusion method and antidiabetic activity was assessed by α-amylase inhibition.Results:Methanolic leaf extracts of both the species of Swertia contain significant antibacterial as well as anti-diabetic potential, whereas methanolic root extracts of both species were found to have potential antioxidant activity. However, Swertia chirayita showed better activities than Swertia cordata although both species have good reputation in traditional Indian medicine.Conclusion:Both the species are having high medicinal potential in terms of their antioxidant, antibacterial and antidiabetic activities. Studies are required to further elucidate antioxidant, anti-diabetic and antibacterial potentials using various in-vitro, in-vivo biochemical and molecular biology techniques.

Multiple-unit tablet of probiotic bacteria for improved storage stability, acid tolerability, and in vivo intestinal protective effect

“…This result might be due to the antimicrobial properties of the aforementioned natural ingredients as reported for swertia herb powder and cinnamon bark powder. 29 , 30 Andilac-S capsule (Il-Yang Pharm., Seoul, Korea), a commercially available product, could not assure the storage stability of L. acidophilus strain under ambient condition ( Figure 6A ), even though these involved the enteric materials.…”

Antifungal potential of Fenugreek Seeds (Trigonella foenum-graecum) Crude Extracts against Microsporum gypseum

“…A huge variety of herbal antifungal agents derived from traditional medicinal plants are existing for the treatment of dermatophytoses (Kimm et al, 2015). In the present scenario, medicinal plants and their phytoconstituents are gaining attention owing to the fact that herbal drugs are lesser in cost, easily accessible, and with fewer or no side effects (Malik et al, 2015). Trigonella foenum graecum (Fenugreek) belong the family Fabaceae is one of the ancient traditional medicinal plants and has a long history of its therapeutic uses (King et al, 2015).…”

Antifungal Potential of Different Extracts of Syzygium Aromaticum Against Microsporum Gypseum

“…A huge variety of herbal antifungal agents derived from traditional medicinal plants are existing for the treatment of dermatophytoses 6 . In the present scenario, medicinal plants and their phytoconstituents are gaining attention owing to the fact that herbal drugs are lesser in cost, easily accessible and with fewer or no side effects 7 . Clove (Syzygium aromaticum) is one of the most valuable spices that have been used from centuries as food preservative and for many medicinal purposes.…”