Evaluation of Antioxidant and Antiulcer Activity of Traditionally Consumed Cucumis melo Seeds

Gill, N.S.; Bajwa, Jasveen; Dhiman, Kunal; Sood, Shailja; Sharma, PD; Singh, Balraj; Bali, M.

doi:10.3923/jpt.2011.82.89

Cited by 33 publications

(14 citation statements)

References 6 publications

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“…Plants contain phytochemicals with various bioactivities including antioxidant, anti inflammatory and anticancer activities. Currently, about 25% of the active component was identified from plants that are used as prescribed medicines [1] . Reactive oxygen species (ROS) exert oxidative damaging effects by reacting with nearly every molecules found in living cells including protein, lipid, amino acids and DNA, if excess ROS are not eliminated by antioxidant system.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical investigation and In vitro antioxidant activity of an indigenous medicinal plant Alpinia nigra B.L. Burtt

Sahoo

Ghosh

Das

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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Objective: To investigate antioxidant potential of methanol extract of Alpinia nigra leaves. Methods: The study was done by using various in vitro methods such as 1,1-diphenyl-2picrylhydrazyl (DPPH), 2,2-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS), nitric oxide and hydrogen peroxide radical scavenging assays. Phytochemical constituents, total phenolic content and total flavonoid content of the extract at different concentrations (10-500 µg/ mL) were determined. Results: Alpinia nigra leaves showed high free radical scavenging activity as evidenced by the low IC 50 values in DPPH (64.51 µg/mL), in ABTS (28.32 µg/mL), in nitric oxide (80.02 µg/mL) and in H 2 O 2 (77.45 µg/mL) scavenging assays. Furthermore the TPC and TFC of the extract were found to be 69.25 mg gallic acid equivalent per gram of extract and 78.84 mg quercetin equivalent per gram of extract respectively. Conclusions: The results of present comprehensive analysis demonstrated that Alpinia nigra leaves possess high phenolic, flavonoid contents and potential antioxidant activity, and could be used as a viable source of natural antioxidants and might be exploited for functional foods and neutraceutical applications.

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Section: Introductionmentioning

confidence: 99%

Phytochemical investigation and In vitro antioxidant activity of an indigenous medicinal plant Alpinia nigra B.L. Burtt

Sahoo

Ghosh

Das

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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“…Migration of neutrophils to the affected area constitutes an important pro-inflammatory factor, as they liberate toxic oxygen radicals in the extracellular medium. C. melo inhibited the leukocyte influx and diminished LTB4 levels, thereby producing antiinflammatory effect [41].…”

Section: Pharmacological Studies Analgesic and Anti-inflammatory Actimentioning

confidence: 99%

“…The mechanism of its gastroprotective activity may be attributed to reduction in vascular permeability, scavenging of free radicals and diminished lipid peroxidation along with strengthening of mucosal barrier. Presence of phytoconstituents, triterpenoids and sterols are responsible for these actions [41].…”

Section: Anti-ulcer Activitymentioning

confidence: 99%

Pharmacognostical and Pharmacological Review of Cucumis Melo L. Including Unani Medicine Perspective

Rehman¹

2018

IPCM

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Cucumis melo which is commonly known as musk melon or Kharbuzah belongs to the family Cucurbitaceae. It is an annual climbing or creeping herb with angular, scabrous stem, simple soft hairy orbicular-reniform leaves and bears tendrils, by which it is readily trained over trellises. Musk melons are extensively cultivated throughout India particularly in the hot and dry NorthWestern areas. Main parts used are pulp, root, seeds and seed oil. It is having diuretic, emmenagogue, and cooling, demulcent, properties. Fruit has been used for several centuries to treat kidney disorders such as kidney and bladder stones, painful and burning micturition, ulcers in the urinary tract, suppression of urine and to treat cough, hot inflammation of the liver, liver and bile obstruction, eczema, etc. The oil from seeds is said to be very nourishing and contains linoleic acid (60-70%), lecithin, cephalin and cerebroside isolated from seed oil. The seeds of melon contain multiflorenol, isomultiflorenol, and 24-methylenecycloartenol.

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“…Plants have always been a major source of medicines, either in the form of traditional preparations or as pure active molecules [1]. Herbal drugs are in demand worldwide in primary health care due to their efficacy, safety and lesser side effects.…”

Section: Introductionmentioning

confidence: 99%

In Vitro Antioxidant Potential of Polyherbal Formulation of Three Different Herbal Drugs

Kumar¹,

Kalia²,

Singh³

2020

IGJPS

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Evaluation of Antioxidant and Antiulcer Activity of Traditionally Consumed Cucumis melo Seeds

Cited by 33 publications

References 6 publications

Phytochemical investigation and In vitro antioxidant activity of an indigenous medicinal plant Alpinia nigra B.L. Burtt

Phytochemical investigation and In vitro antioxidant activity of an indigenous medicinal plant Alpinia nigra B.L. Burtt

Pharmacognostical and Pharmacological Review of Cucumis Melo L. Including Unani Medicine Perspective

In Vitro Antioxidant Potential of Polyherbal Formulation of Three Different Herbal Drugs

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