Evaluation of antioxidant activity of flower and seed oil of Azadirachta indica A. juss

Nahak, Gayatri; Sahu, Rajani Kanta

doi:10.31018/jans.v3i1.158

Cited by 40 publications

(32 citation statements)

References 15 publications

(9 reference statements)

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“…Experimentation was made to evaluate the antioxidant activity of the flowers and seed oil of neem plant Azadirachta indica A. Juss. and results revealed that ethanolic extract of flowers and seed oil at 200 μ g/mL produced the highest free radical scavenging activity with 64.17 ± 0.02% and 66.34 ± 0.06%, respectively [ 26 ].…”

Section: Therapeutic Implications Of Neem and Its Various Ingrediementioning

confidence: 99%

Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment

Alzohairy

2016

Evidence-Based Complementary and Alternative Medicine

532

308

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Neem (Azadirachta indica) is a member of the Meliaceae family and its role as health-promoting effect is attributed because it is rich source of antioxidant. It has been widely used in Chinese, Ayurvedic, and Unani medicines worldwide especially in Indian Subcontinent in the treatment and prevention of various diseases. Earlier finding confirmed that neem and its constituents play role in the scavenging of free radical generation and prevention of disease pathogenesis. The studies based on animal model established that neem and its chief constituents play pivotal role in anticancer management through the modulation of various molecular pathways including p53, pTEN, NF-κB, PI3K/Akt, Bcl-2, and VEGF. It is considered as safe medicinal plants and modulates the numerous biological processes without any adverse effect. In this review, I summarize the role of Azadirachta indica in the prevention and treatment of diseases via the regulation of various biological and physiological pathways.

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Section: Therapeutic Implications Of Neem and Its Various Ingrediementioning

confidence: 99%

Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment

Alzohairy

2016

Evidence-Based Complementary and Alternative Medicine

532

308

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“…The unsaponifiable fraction contains sterols and tocopherols (with b-sitosterol and g-tocopherol as the major sterol and tocopherol components, respectively) (Djibril et al, 2015). It also contains vitamin E, phenols, and many triterpenoids of which azadirachtin is the most well known and studied (Devi and Maji, 2011;Nahak and Sahu, 2011).…”

mentioning

confidence: 99%

Neem Oil Used as a “Complex Mixture” to Improve In Vitro Shoot Proliferation in Olive

Micheli

Silva

Farinelli

et al. 2018

horts

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Shoots of the olive cultivar Moraiolo were previously cultured in aseptic conditions on Olive Medium (OM), with the addition of 4 mg·L−1 of zeatin, 30 g·L−1 of sucrose, and 7 g·L−1 of agar. Then, 1-cm long uninodal explants with two leaves and two axillary buds were excised from the proliferated masses and placed on the same proliferation medium enriched with four concentrations of neem oil (0—control, 0.1, 0.5, and 1.0 mL·L−1), added before sterilization. The addition of 0.1 mL·L−1 of neem oil to the medium gave an improvement in shoot regeneration. More vigorous shoots (longer proliferated shoots) were obtained along with a higher number of nodes (multiplication rate). Overall, there was a significant increase in the total fresh and dry proliferated weights. To our knowledge, this is the first report showing a strong and beneficial effect of neem oil, used as a “complex mixture,” on in vitro plant regeneration.

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“…The antioxidant activity of all the different extract samples is measured by the DPPH radical scavenging method (18) To support our antioxidant results previously also several antioxidant activities of neem (6,(19)(20)(21), tulsi (9,(22)(23)(24) and cow urine (5,(25)(26)(27) are studied. The synergistic antioxidant activity of tulsi, ginger, tea, and black pepper is studied by Gupta et al (28)…”

Section: Antioxidant Activitymentioning

confidence: 57%

Study of In-vitro Antioxidant and Antibacterial activity of leaf extract of Azadirachta indica, and Ocimum sanctum in different organic solvents and Cow urine

Adhikari

Rana

Oli

et al. 2020

J. Drug Delivery Ther.

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Background: Neem (Azadirachta indica), Tulsi (Ocimum sanctum) and Cow urine (Bos indicus) has been widely used as a therapeutic potential or additive agent in different ethnomedicinal practices as well as modern science also proved its therapeutic potential to treat various diseases and balance the body conditions. Aims: Alone study on Neem, Tulsi and Cow urine (CU) has been widely performed but this study aims to evaluate the individual as well as synergistic antioxidant and antibacterial activity of Neem, and Tulsi’s leaves extract in different organic solvents and Cow urine. Materials and Methods: Antioxidant activity was carried out by using 2,2-Diphenyl1-picrylhydrazyl (DPPH) radical scavenging activity and the antibacterial activity was tested by the agar disc diffusion method against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli, Proteus vulgaris and Klebsiella species) bacteria. Results: The antioxidant and antibacterial activity is concentration-dependent. The neem extract in chloroform shows the highest ZOI against S. aureus (14±2). Similarly, the neem extract in cow urine (8±0.86) and tulsi extract in methanol (8±1.04) shows the highest ZOI against E. coli. Against K. species cow urine is most effective (9±0.29) followed by neem extract in chloroform and cow urine (8±0.77). In P. vulgaris almost all sample shows ZOI around 7 mm. In synergistic antibacterial study tulsi and neem extract in cow urine shows the highest ZOI against E. coli (12±1.75) and P. vulgaris (10±1.44). The tulsi and neem extract in hexane is not effective against S. aureus and E. coli but effective in P. vulgaris and K. species (ZOI 7 mm). Tulsi and neem extract in chloroform, methanol, and cow urine show similar ZOI (9 mm). In DPPH free radical scavenging activity the methanolic extract of tulsi shows the highest inhibition of free radicle (96.35±0.001), followed by methanolic extract of neem (84.85±0.042). The fresh cow urine inhibits (25.19±0.037) followed by neem extract in chloroform (24.53±0.003), neem extract in cow urine (21.8±0.012), tulsi extract in chloroform (20.86±0.047), tulsi extract in hexane (19.5±0.031), tulsi extract in cow urine (18.33±0.023) and the least inhibition by neem extract in hexane (6.74±0.042).

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Evaluation of antioxidant activity of flower and seed oil of Azadirachta indica A. juss

Cited by 40 publications

References 15 publications

Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment

Therapeutics Role of Azadirachta indica (Neem) and Their Active Constituents in Diseases Prevention and Treatment

Neem Oil Used as a “Complex Mixture” to Improve In Vitro Shoot Proliferation in Olive

Study of In-vitro Antioxidant and Antibacterial activity of leaf extract of Azadirachta indica, and Ocimum sanctum in different organic solvents and Cow urine

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