Evaluation of antinociceptive and anti-inflammatory potential of flower extract Tecoma stans

Kameshwaran, S.; Suresh, V.; Arunachalam, G.; Frank, Patricia; Manikandan, Velu

doi:10.4103/0253-7613.99352

Cited by 18 publications

(13 citation statements)

References 5 publications

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“…Phytochemical investigation of aqueous and ethanolic extracts of Potentilla anserina Linn have revealed the presence of various phytoactive constituents such as alkaloids, saponins, flavonoids, glycosides, tannins, phenolic compounds and steroids. Earlier studies indicate β-sitosterol 1 , flavonoids 4 , phenolic compounds 29 , and tannins 30 may be responsible for anti-inflammatory activity. These plant extracts also contain the similar phyto constituents which was responsible for the activity.…”

Section: Resultsmentioning

confidence: 99%

“…Currently available anti-inflammatory agents are associated with unwanted side effects-gastrointestinal damage and have their own limitations 2 . Plants which are reported to have anti-inflammatory activity include Punica granatum 3 , Tecoma stans 4 , Polyalthea longiflora 5 , Ficus religiosa 6 , Curcuma longa L 7 , Aloe vera 8 , Gmelina asiatica 9 , Caesalpinea pulcherrima Linn 10 , Sida rhombifolia 11 , Butea frondosa 12 , Vitex leucoxylon Linn 13 , Ricinus communis 14 , Hedychium spicatum 15 , Desmodium gangeticum 16 , Argyreia speciosa 17 , Randia dumetorum 18 , plantago major L 19 , Broussonetia papirifera 20 etc. There is a growing interest in the pharmacological evaluation of various plants used in Indian traditional systems of medicine 21 .…”

Section: Introductionmentioning

confidence: 99%

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Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

Manisha¹,

Sumanth²

2018

AJPTR

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This study was taken up to assess the aqueous and ethanol extracts of whole plant of Potentilla anserina Linn for anti-inflammatory activity in rats by Formalin induced paw oedema method.Animals were divided into 6 groups of 6 rats. Groups 1 and 2 served as Formalin induced control and standard (Diclofenac 5 mg/Kg, i.p.) respectively. Groups 3 and 4 were treated, orally with aqueous extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. Groups 5 and 6 were administered, orally with ethanol extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. The paw volume was measured at 0, 1, 2, 3 and 4 hr after Formalin injection.The actual edema volume was calculated. The data was expressed as mean ± S.E.M. The statistical analysis was done by means of ANOVA followed by Dunnett"s post hock test. The aqueous and ethanol extracts of whole plant of Potentilla anserina Linn produced significant reduction of edema in the rats. Ethanol extract of whole plant of Potentilla anserina Linn revealed significant anti-inflammatory activity.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

Manisha¹,

Sumanth²

2018

AJPTR

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“…The E(PA) indicated the remarkable rise in percentage inhibition. Previous phytochemical studies indicated presence of β-sitosterol, [1] (in Typha angustifolia), flavonoids, [11] (in Tecoma stans), phenolic compounds [12] (in Polyalthea longiflora), tannins [13] (in Ficus religiosa) are responsible for anti-inflammatory activity. Previous literature search and prior studies have indicated presence of β-sitosterol [4] in Barleria longiflora L.f. and tannins, flavonoids, β-sitosterol in Potentilla anserina Linn [5] .…”

Section: Resultsmentioning

confidence: 99%

EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF BARLERIA LONGIFLORA L.f. AND POTENTILLA ANSERINA LINN

Manisha¹

2017

WJPR

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Aim: Evaluation of aqueous and ethanol extracts of leaves of Barleria longiflora L.f. and whole plant of Potentilla anserina Linn for antiinflammatory activity using Carrageenan induced paw oedema in rats. Materials and method:Animals were divided into 10 groups of 6 rats. Groups 1 and 2 served as Carrageenan induced control and standard (Diclofenac 5 mg/Kg, i.p.) respectively. Groups 3 and 4 were treated, orally with aqueous extract of Barleria longiflora L.f. with 100 and 400 mg/kg b.w, respectively. Groups 5 and 6 were administered, orally, ethanol extract of Barleria longiflora L.f. with 100 and 400 mg/kg b.w, respectively. Groups 7 and 8 were received, orally, aqueous extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. Groups 9 and 10 were administered, orally, ethanol extract of Potentilla anserina Linn of 100 and 400 mg/kg b.w, respectively. The paw volume was measured at 0, 1, 2, 3 and 4 hr after carrageenan injection.The actual edema volume was calculated. The data was expressed as mean ± S.E.M. The statistical analysis was done by means of ANOVA followed by Dunnett's post hock test. Results:The aqueous and ethanol extracts of leaves of Barleria longiflora L.f. and whole plant of Potentilla anserina Linn exhibited significant reduction of edema in the rats. Conclusion:Ethanol extract of whole plant of Potentilla anserina Linn revealed superior anti-inflammatory activity.

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“…Many biological activities were confirmed, especially those based on folk use as a hypoglycemic and hypolipidemic agent for diabetes mellitus [32]. In addition, Tecoma stans has wound-healing [33], antioxidant, antimicrobial [34], analgesic, anti-inflammatory [35], nephroprotective [36], and cardioprotective activities [29].…”

Section: Introductionmentioning

confidence: 99%

Anti-Oral Pathogens of Tecoma stans (L.) and Cassia javanica (L.) Flower Volatile Oils in Comparison with Chlorhexidine in Accordance with Their Folk Medicinal Uses

2019

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Background and Objectives: Teeth decay and plaque are complicated problems created by oral pathogens. Tecoma stans (L.) and Cassia javanica (L.) are two ornamental evergreen plants widely distributed in Egypt. These plants are traditionally used for oral hygienic purposes. This study aims to elucidate the volatile oil constituents obtained from the flowers of these plants and evaluate the antimicrobial activity of these volatile oils against specific oral pathogens in comparison to chlorhexidine. Materials and Methods: The flowers obtained from both plants were extracted by n-hexane. GC-MS spectrometry was used to identify the constituents. Minimum inhibitory concentrations (MICs) were measured using tetrazolium salt (2,3-bis[2-methyloxy-4-nitro-5-sulfophenyl]-2H-tetrazolium-5-carboxanilide) (XTT). Results: GC-MS analysis revealed the presence of 32 and 29 compounds, representing 100% of the volatile constituents of Tecoma stans and Cassia javanica, respectively. The GC-MS analysis showed more than 60% of the volatile oil constituents are represented in both plants with different proportions. Chlorhexidine exerted stronger activity than tested plants against all microorganisms. Cassia javanica flower extract was more active against all tested microorganisms than Tecoma stans. Of note was the effect on Streptococcus mutans, which was inhibited by 100% at 12.5 and 25 µg/mL of Cassia javanica and Tecoma stans, respectively. The growth of Lactobacillus acidophilus was also completely inhibited by 25 µg/mL of the Cassia javanica extract. MIC90 and MIC were also calculated, which revealed the superiority of Cassia javanica over Tecoma stans against all tested oral pathogens. Conclusion: Cassia javanica flower volatile oils showed a potential anti-oral pathogen activity at relatively low concentrations. Also, Cassia javanica and Tecoma stans demonstrated a strong activity against tooth decay’s notorious bacteria Streptococcus mutans. Both plants can be potential substituents to chlorhexidine. Formulating the constituents of these plants in toothpastes and mouthwashes as anti-oral pathogen preparations can be an interesting future plan.

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Evaluation of antinociceptive and anti-inflammatory potential of flower extract Tecoma stans

Cited by 18 publications

References 5 publications

Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

Anti-Inflammatory Activity of Aqueous And Ethanolic Extracts of Potentilla Anserina Linn

EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF BARLERIA LONGIFLORA L.f. AND POTENTILLA ANSERINA LINN

Anti-Oral Pathogens of Tecoma stans (L.) and Cassia javanica (L.) Flower Volatile Oils in Comparison with Chlorhexidine in Accordance with Their Folk Medicinal Uses

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