Evaluation of antimicrobial and synergistic effects of selected medicinal plants of Hail area with antibiotics

Abstract

In this study, the antibacterial activity of selected medicinal plants and their synergistic effect with antibiotics were investigated. Different antibiotic resistant bacterial species were employed including: Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumonia), Acinetobacter baumannii (A.baumannii), Pseudomonas aeruginosa (P. aeruginosa), Staphylococcus aureus (S. aureus) and Salmonella spp. The results indicated that methanol extracts of most of the tested plants inhibited growth of the tested bacteria, however, the highest inhibition was by Senna followed by Harmal, saffl ower and Guaada, where the inhibition zone diameter was 8 mm, 4 mm, 3 mm, 2 mm and 2 mm, respectively. The synergism between plants extract and antibiotics resulted in inhibition of the tested organisms; generally, the synergism with Harmal extract was more effective in inhibition of antibiotic-resistant bacteria, followed by Senna and fi nally Saffl ower. The outcomes additionally demonstrated that methanolic concentrate of the plant has more inhibitory impact than that of the water extract. Further investigation of the plants extract to seclude and recognize the dynamic fi xings is prescribed.

Antibacterial effect of Asphodelus fistulosus aqueous and ethanolic crude extracts on gram positive and gram negative bacteria

“…in Jordan and few studies were done around the world (Malmir et al, 2018). Leaves water extract of A. fistulosus did not inhibit growth of E. coli while the methanolic extract of the same plant part did (Sulieman et al, 2017)…”

“…The toothache is treated traditionally using seeds (Jafri And EL-Gadi, 1978;Agrawal, 1990). In Saudi Arabia, aqueous and methanolic leave extracts of A. fistulosus was studied on four types of bacteria by Sulieman et al (2017) while Alam et al (2018) studied antimicrobial activities of seed ethanolic extract of A. fistulosus. In 2009, the roots usage was reported by Leonti et al (2009) to treat respiratory ailments, against burns and as a cutaneous disinfectant.…”

Phytochemical composition, Antimicrobial, GC-MS analyses and computational modeling of Fenugreek (Trigonella foenum-graecum L) Seeds

“…The many healthful components of the oil are magnesium, iron, manganese, fiber, and many more. The oil's antibacterial properties effectively kill some kinds of bacteria and fungi [Sulieman et al 2017a;Sulieman et al 2023].…”

Phytochemical Screening, Antimicrobial, and Antioxidant Activities of Root and Leaf Extracts of Leucas Aspera

“…It is well known that several medicinal plants have been used to treat microbial infections from 1000 years [1,2]. A number of studies reported the antimicrobial properties of plants [3][4][5][6][7][8][9]. In addition to medicinal value, there is an increasing interest toward natural antioxidants present in plants.…”