Evaluation of antimicrobial activity of a fast-setting bioceramic endodontic material

Abstract

Purpose To evaluate the antimicrobial activity of the fast-setting bioceramic iRoot Fast Set Root Repair Material (iRoot FS) and two other calcium silicate cements. Methods The antimicrobial activity of iRoot FS, ProRoot MTA and Biodentine against E. faecalis and P. gingivalis were evaluated in this study. The materials were freshly mixed or set for 1 and 7 days to conduct the agar diffusion test, direct contact test and carry-over effect test, and the pH values were also measured. The data were analyzed by an analysis of variance and two-way ANOVA (α = 0.05). Results In the direct contact test, all three materials showed good antibacterial activity after setting for 20 minutes. The antibacterial properties of the three materials decreased with the increase of setting time. The suspension of all the three materials showed high pH values (11–12). With the extension of setting time, the pH of iRoot FS and Biodentine slightly decreased. Conclusion Fresh iRoot FS, Biodentine, and MTA killed E. faecalis and P. gingivalis effectively, and the antimicrobial effect of all the three materials decreased over 1 and 7 days after mixing. All three materials showed a tendency of alkalinity which last for at least 7 days after setting.

Fracture Resistance of Molars With Simulated Strip Perforation Repaired With Different Calcium Silicate-Based Cements

“…According to the manufacturer, bioceramic putty is composed of calcium silicate, monobasic calcium phosphate, zirconium oxide, tantalum oxide, and filler agents [ 12 ]. Bioceramics are biocompatible materials that have antibacterial properties similar to those of MTA [ 13 ], and minimal or sometimes no inflammatory response is observed in periodontal tissues after applying these materials [ 14 ]. In vitro studies have shown that bioceramic putty has a similar sealing ability compared with MTA [ 15 , 16 ].…”