Evaluation of Antihelmintic Activity of Indigenous Plants Found in India Including Butea Monosperma, Origanum Majorana, Piper Longum and Embelia Ribes And GC-MS Phytochemical Analysis of Plant Extracts

Giri, Kiran R.; Singh, Aradhana; Palandurkar, Kamlesh; Banerjee, Tuhina; Chaurasia, Satish

doi:10.5530/pj.2021.13.186

Cited by 3 publications

(2 citation statements)

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“…These compounds are widely employed as an active component in both traditional and modern medicine to treat a variety of illnesses [2,3]. The World Health Organization (WHO) asserts that medicinal plants are the greatest source of a broad range of medications [4], with more than 80% dependency on traditional medicine [4]. The therapeutic value of plants is primarily attributed to the existence of bioactive compounds such as tannins, phenolics, flavonoids, glycosides, alkaloids, and terpenoids [5,6].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of TPC, TFC, and Antioxidant Activity of Extracts of Piper longum L.

Panta,

Dhital,

Budha

et al. 2024

AJACR

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Medicinal plants have been crucial in treating various diseases since ancient times. This study focuses on identifying the phytochemicals in Piper longum L. extracts along with studying their biological activities. The powdered fruit of P. longum was sequentially subjected to ultrasonic extraction utilizing solvents with increasing polarity, starting from hexane and progressing through chloroform, ethyl acetate, and finally, methanol. The phytochemical analysis of extracts exhibited the presence of all tested classes of phytocompounds except saponins. The higher phenolic content (TPC) was observed in the methanol extract (53.38 mg GAE/g), whereas the chloroform extract had a TPC value of 8.51 mg GAE/g. Conversely, the chloroform extract exhibited a higher total flavonoid content (TFC) of 12.09 mg QE/g compared to the methanol extract's 7.44 mg QE/g. The antioxidant assay demonstrated the moderate antioxidant potential of the methanol extract. This study recommends further biological tests and experimental verifications to use this plant for drug discovery.

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Section: Introductionmentioning

confidence: 99%

Evaluation of TPC, TFC, and Antioxidant Activity of Extracts of Piper longum L.

Panta,

Dhital,

Budha

et al. 2024

AJACR

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“…Several ethnomedicinal studies confirmed these remedies to treat parasitic infections in rural communities, which exhibited potent anthelmintic activity against Raillietina spp. (Giri et al, 2021). Kar et al previously reported the in vitro anthelmintic activity of gold nanoparticles from the fungus Nigrospora oryzae on cestode parasites.…”

Section: Introductionmentioning

confidence: 99%

A facile green synthesis approach to silver nanoparticles using calyx fromAbelmoschus esculentusand its anthelmintic activity

Majumdar

Kar

2023

Preprint

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In recent years, technology pertaining to nanobiomaterials has taken rapid strides, with the development of novel materials having unique properties. Silver nanoparticles (AgNPs) have gained attention among these materials due to their high chemical stability, surface-to-volume ratio, and strong antimicrobial activity. The traditional method for synthesizing AgNPs involves toxic chemicals, which can have negative environmental impacts and pose health risks. Hence, there is a growing need for green synthesis methods for AgNPs that are environmentally friendly and safe for animal and human health. In this study, we explore the green synthesis of AgNPs using calyx fromAbelmoschus esculentus, also known as okra, as an anthelmintic.Raillietinaspp. is a common poultry parasite causing significant economic losses to the livestock industry. It is a major cause of ailment and mortality in livestock, deterring the host health. While chemical-based anthelmintic drugs are available, the increasing prevalence of drug-resistant parasite strains has made searching for new and effective treatments imperative. Although ethnomedicine has been promising for treating various diseases, including parasitic infections, nanoparticles have emerged as a viable alternative to traditional anthelmintic curative development. Our study aims at investigating the recent advances in nanomedicine, particularly AgNPs, as anthelmintic agents, which has shown remarkable alterations in the levels of tegumental enzymes, eventually leading to their paralysis and death. We discuss the mechanisms of action of AgNPs againstRaillietinaspp. and highlight the potential benefits of using biosynthesized curatives that interfere with the host-parasite interface to treat parasite-related disorders.

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