Evaluation of antidiarrhoeal profile of Jussiaea suffruticosa Linn. extract in rats

Murugesan, T.; Ghosh, L. K.; Mukherjee, Kakali; Das, Joydeep; Pal, Mintu; Saha, B. P.

doi:10.1002/1099-1573(200008)14:5<381::aid-ptr590>3.0.co;2-p

Cited by 36 publications

(26 citation statements)

References 2 publications

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“…[61,62] terpineolene, β-caryophyllene, p-cymene, sabinene, bornyl acetate, β-cubebene and a trace of α-pinene. [65] Sesquiterpenes (germacrene D) constituted the major part of the volatiles in…”

Section: Chemical Constituentsmentioning

confidence: 72%

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Paarakh¹

2017

WJPPS

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Medicinal herbs are the significant source for treatment of number of diseases, one such is Diuretics. Mono and poly-herbal preparations have been used as diuretics. According to estimate, more than 650 mono and poly-herbal preparations in the form of decoction, tincture, tablets and capsules are from more than 75 plants that are in clinical use. There exist a large number of studies which supports the diuretic effects of traditional herbal medicines. Herbal medicine have been the most commonly prescribed medications for diuretics. They inhibit electrolyte reabsorption from the lumen of the nephron, increasing osmolarity, enhancing water and electrolyte excretion. It is important to note that there is a delicate balance between dietary sodium intake and sodium loss. If the balance is compromised and there is a greater intake of sodium into the body, but not enough sodium removal, complications of fluid overload occur, such as oedema, pulmonary oedema or high blood pressure. When there is greater removal of sodium, but not enough sodium intake, complications of fluid depletion take place, such as renal failure or reduced output of blood from the heart. The ability to induce a negative fluid balance has made diuretics useful in the treatment of a variety of conditions, particularly in hypertension and oedematous states. This review gives information about few herbal plants which are used traditionally in Karnataka as diuretics. There are a large number of studies which supports the diuretic effects of traditional herbal medicines which is presented along with chemical constituents and other pharmacological action of the plants.

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Section: Chemical Constituentsmentioning

confidence: 72%

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Paarakh¹

2017

WJPPS

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“…[1,2,3] Centella asiatica L. has been used as a medicinal herb for thousands of years in India, China, Srilanka and Nepal for treating skin problems, to heal wounds, for revitalizing the nerves and brain cells, hence primarily known as a "Brain food" in India. [4,5,6] Centella asiatica (Linn.)…”

Section: Among the Several Plants Boerhaavia Verticillata Urtica DImentioning

confidence: 99%

“…Most diuretic drugs derived from chemical sources are associated with adverse effect on quality of life including impotence, hyperglycemia, ototoxicity, gout and fatigue etc. [1,3] Many indigenous drugs have been claimed to have diuretic effect in Ayurvedic system.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Diuretic Activity of Aqueous Extract of Leaves of Centella Asiatica

Debnath¹

2017

WJPR

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Aim: The present study was undertaken to investigate diuretic effect of aqueous extracts of the dried leaves of Centella asiatica in normal rats.Centella asiatica (L.) is a perennial herb, faintly aromatic and used traditionally for various medicinal properties from ancient times.Demand for herbal formulation is growing all over the world as they are considered to be safer with fewer side effects than the synthetic 3.

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“…The animals were separated into 10 groups of 6 rats per group and diuretic activity was performed according to the method described by Lipschitz et al (1943) with slight modification by Murugesan et al (2000). The animals were deprived of food and water for 18hrs prior to the experiment.…”

Section: Diuretic Activitymentioning

confidence: 99%

Diuretic, Antidiuretic and Laxative Activities of Anthocleista Vogelii Extracts in Rats

Anyanwua

Onyeneke

Ofoha

et al. 2017

Afr J Tradit Complement Altern Med

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Background: Anthocleista vogelii Planch is a medicinal plant used by traditional healers in the treatment of Malaria, hypertension, ulcer, obesity, diabetes, and as a diuretic and purgative in Africa. Therefore, the present study sought to evaluate the diuretic, antidiuretic and laxative activities of the root bark of A. vogelii extracts and fractions in male SpragueDawley rats. Materials and methods: Sixty rats were placed in 10 groups which included: control (normal saline), furosemide/sodium picosulfate (25 mg/kg) as standard drugs, methanol extracts (250 mg/kg and 500 mg/kg), and 125 mg/kg and 250 mg/kg of saponin, flavonoid and neutral alkaloid fractions of A. vogelii. The drugs/extracts/fractions were administered orally using normal saline as the vehicle. Results: The 500 mg/kg methanol extracts (ME) significantly increased (p<0.05) the urine volume and electrolytes (Na + , K + and Cl -) excreted, while 125 mg/kg and 250 mg/kg flavonoid fraction (FF) decreased significantly (p<0.05) urine volume and electrolytes (Na + , K + and Cl -) excreted, but doses of saponin fraction (SF) and neutral alkaloid fraction (NAF) had no significant difference (p<0.05) compared to the control after 5 hrs. ME, SF, NAF significantly increased (p<0.05) the fecal output of the animals when compared to the control, while FF showed no significant difference (p<0.05) after 8 hrs of administration. Conclusions: This study determined that ME revealed diuretic activity, although not remarkable to furosemide, while FF showed antidiuretic activity, and potent laxative activities were discovered in ME and SF of A. vogelii.

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Evaluation of antidiarrhoeal profile of Jussiaea suffruticosa Linn. extract in rats

Cited by 36 publications

References 2 publications

A Review on Medicinal Plants Used as Diuretics From Karnataka State

A Review on Medicinal Plants Used as Diuretics From Karnataka State

Evaluation of Diuretic Activity of Aqueous Extract of Leaves of Centella Asiatica

Diuretic, Antidiuretic and Laxative Activities of Anthocleista Vogelii Extracts in Rats

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