Evaluation of Antibiotic Consumption in a University Hospital

Yılmaz, Gülden; Oztürk, Elif Mukime; Ayhan, Müge; Coşkun, Belgin; Azap, Alpay

doi:10.5152/kd.2014.31

Cited by 3 publications

(5 citation statements)

References 8 publications

(13 reference statements)

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“…In Pakistan, Nigeria and Tanzania, higher rates of antibiotic use were reported ranging from 62% to 80.1% [ 31 – 33 ]. While the rate of antibiotic use in our study was similar to previous studies in our country [ 7 , 28 , 29 ], it was observed with a higher rate than some of the European countries, it is observed lower than in Asia and some European countries [ 14 , 32 , 34 ].…”

Section: Discussionsupporting

confidence: 90%

“…In our study, the rate of inappropriate use was 20% and was quite lower than previous studies. In the previous studies, rates of inappropriateness varied between 25.8% and 54.3% from our country [28][29][30]. Ingram et al reported 47% inappropriate antibiotic usage [5].…”

Section: Discussionmentioning

confidence: 68%

“…In present study, 33.8% of hospitalized adult patients were using at least one antibiotic. In previous studies from our country, the antibiotic prescription was reported at different rates varying from 27.2% to 44.8% [15,[27][28][29][30]. In a study from Australia, a rate of 43% antibiotic use was reported, while in a multicenter study including 13 centers in China, this rate was reported as 56% [5,14] In a study evaluating antibiotic use in 53 countries in Europe, rates of antibiotic use were reported as 15.6% in Northern Europe and 43.9% in Eastern Europe.…”

Section: Discussionmentioning

confidence: 92%

“…Unnecessary use and inappropriate longer duration were the most common causes of inappropriate use in our study. In previous studies, unjustified and unnecessary use, incorrect choice of antibiotics, incorrect dose and duration, treatment of colonizing and contamining agents were reported as common reasons for inappropriate antimicrobial use [ 5 , 29 , 38 ]. In our study, the rates of incorrect agent choice and incorrect dose were lower.…”

Section: Discussionmentioning

confidence: 99%

“…This study is the first point prevalence study performed in the highest number of patients as a single center in our country. Point prevalence surveys are inexpensive, effortless and easily repeatable type of studies [ 29 , 48 ]. It may not be appropriate to make a comparison between different centers as the characteristics of the centers may vary.…”

Section: Discussionmentioning

confidence: 99%

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Point prevalence of antibiotic usage in major referral hospital in Turkey

Ayhan,

Coşkun,

Kayaaslan

et al. 2024

PLoS ONE

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Introduction The most important and undesirable consequence of inappropriate antibiotic use is the spread of antibiotic resistance, increased adverse effects, increased mortality and healthcare costs. We aimed to assess antibiotic usage characteristics in inpatient setting in our center. Materials and methods A one-day, single center point-prevalence study was carried out on June 9th 2021, in Ankara City Hospital in Turkey. Data of antibiotic consumption, appropriateness of usage and predictors of inappropriate use in adult patients were evaluated. Results Out of 2640 adult patients, 893 (33.8%) were receiving at least one antibiotic. A total of 1212 antibiotic prescriptions with an average of 1.44±0.64 were found. Antibiotics were most commonly used for therapeutic purpose (84.7%), followed by surgical prophylaxis (11.6%). Majority of therapeutically used antibiotics were empirical (67.9%). Infectious diseases consultation was present in 68.3% with a compliance rate of 95.7%. Rate of inappropriate use was 20%. The most frequent cause of inappropriateness was unnecessary use (52.5%). Most commonly and most inappropriately used antibiotics were carbapenems (17.5%) and first generation cephalosporins (38.7%), respectively. Most of the inappropriateness observed in first-generation cephalosporins was due to inappropriate longer surgical prophylaxis. While age is an independent risk factor for inappropriate antibiotic use (p = 0.042), COVID-19 unit admission, use for therapeutic purpose and infectious diseases consultation were protective factors (p<0.001, p<0.001, p<0.001). Conclusion Rate of inappropriate use was low, but inappropriate surgical prophylaxis remains an important problem in surgical units. There is a considerable need to implement an antimicrobial stewardship program that focuses on surgical prophylaxis practices.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 68%

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Point prevalence of antibiotic usage in major referral hospital in Turkey

Ayhan,

Coşkun,

Kayaaslan

et al. 2024

PLoS ONE

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The point prevalence and inappropriateness of antibiotic use at hospitals in Turkey: a systematic review and meta-analysis

Selçuk

2021

Journal of Chemotherapy

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Üçüncü basamak bir hastanede cerrahi profilaktik antibiyotik kullanımının değerlendirilmesi

KUBAT

SUNTUR

UĞURBEKLER

2022

Mersin Üniversitesi Sağlık Bilimleri Dergisi

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Amaç: Antibiyotik profilaksisi, cerrahi alan enfeksiyonlarını önlenmeye yönelik temel uygulamalardan birisidir. Akılcı cerrahi profilaksi için doğru antibiyotik, doğru zamanlama ile doğru dozda verilmelidir. Bu çalışmada, hastanemizdeki cerrahi profilaksi amacıyla antibiyotik kullanımının, hastanemiz cerrahi antibiyotik profilaksi rehberine uygunluğunun incelenmesi amaçlanmıştır. Yöntem: Adana Şehir Eğitim ve Araştırma Hastanesi’nde 01.05.2019-20.10.2019 tarihleri arasında, sekiz farklı cerrahi klinikte ameliyat edilmiş olan erişkin hastalar çalışmaya dahil edildi. Bu hastalara uygulanan profilaktik antibiyotikler, içerik, uygulanma zamanlaması, doz ve kullanım süresi bakımından retrospektif olarak incelenerek, hastanemizin cerrahi profilaksi rehberine uygunluğu açısından değerlendirildi. Bulgular: Çalışmaya 233’ü (%48.54) kadın, 247’si (%51.46) erkek olmak üzere 480 hasta dahil edildi. Yaş ortalaması 42.96±16.58 yıldı. Operasyon süresi ortalama 104.66±52.98 dakikaydı. Profilaksi, hastaların %35.9’unda (172/480) cerrahi profilaksi rehberine uygun; %64.16’sında (308/480) uygun olmayan şekilde yapılmıştı. Cerrahi profilaksi rehberine uyumsuzluk nedenlerinin %24.4’ünü uzamış profilaksi, %19.2’sini profilaksi gerekirken verilmemesi, %12.5’ini dört saatten uzun süren ameliyatlarda ek doz verilmemesi, %11’ini antibiyotiğin insizyondan 24 saat önce başlanmış olması, %11’ini insizyondan önce yapılmayıp ameliyat sonrası yapılması, %8.1’ini içerik olarak yanlış antibiyotik seçimi oluşturmaktaydı. Sonuç: Bu çalışmada; cerrahi profilaksi rehberine uyumsuzluk nedenleri arasında en çok gözlenen ameliyat sonrası dönemde gereksiz olarak antibiyotiğe devam edilmesiydi. İçerik olarak yanlış antibiyotik seçimi ve uygulama zamanlaması ile ilgili uyumsuzluklar daha az orandaydı. Uzamış profilaksi tutumundan vazgeçilmesi başta olmak üzere, cerrahi profilaksi rehberine tam uyum sağlanmasının, hem güvenli cerrahi hem de akılcı antibiyotik kullanımı açısından önemli olduğuna ikna edici faaliyetlere ihtiyaç duyulduğu görüldü.

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Evaluation of Antibiotic Consumption in a University Hospital

Cited by 3 publications

References 8 publications

Point prevalence of antibiotic usage in major referral hospital in Turkey

Point prevalence of antibiotic usage in major referral hospital in Turkey

The point prevalence and inappropriateness of antibiotic use at hospitals in Turkey: a systematic review and meta-analysis

Üçüncü basamak bir hastanede cerrahi profilaktik antibiyotik kullanımının değerlendirilmesi

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