Evaluation of Antibacterial and Anthelminthic Activity of Fermented Ayurvedic Formulations

Abstract

Traditional medical care systems are believed to incorporate natural ingredients into potential medicines. Lack of standardization has led Ayurveda as a marginalized medical practice. This study aims to throw some light on selected fermented polyherbal formulations against a rare but fatal infection causing C. violaceum and intestinal E. coli flora. The process of fermentation transforms the actual phytochemicals into a therapeutic molecule. Alcohol produced as a result of fermentation and the phytochemicals exhibits an antibacterial property. Determination of phytochemicals in the formulations and alcohol content makes bacteria and helminths susceptible to the treatment. Phenols, alkaloids and steroids were found to be positive for all the formulations, i.e., Chandanasava, Punarnavasava and Vidangarishta. Assessment of fermented Ayurvedic formulation reveals that it is a potent vermifuge with the goodness of nature. Among the formulations Vidangarishta was found to be most potent in paralysing worms. The results of the study implicate cytotoxic effects of these formulations against C. violaceum and intestinal E. coli flora and also their ability to act as an anthelminthic agents.

Pharmacological Potential of Polyherbal Ayurvedic Formulations – A Review

“…Parasitic infections lead to loss of appetite, anemia, blotting, etc. [66]. Administration of vidangarishta helps to treat urinary disorders, appetite problems, prostate enlargement, and skin disorders.…”