Evaluation of Anti-urolithiasis Activity by Nucleation Assay

Abstract

Many causes, including the efficiency of plant medicines and their lower side effects when compared to contemporary medications, have contributed to the current rebirth of plant therapies. Given the current situation, basic scientific research on the therapeutic herbs utilized in indigenous systems is urgently needed. The purpose of this review is to provide information on current developments in the study of medicinal plants recognized for their antiurolithiatic properties. This could assist researchers in determining and creating suitable lead compounds or plant products that are advantageous in the treatment of urolithiasis. A series of physicochemical processes, including supersaturation, nucleation, growth, aggregation, and retention inside the kidneys, combine to form kidney stones. In developed nations, 10–12% of people suffer from urinary stones. There are very few places in the world where stone disease is uncommon, such as Germany and the coastal regions of Japan. Thus, the purpose of this review is to provide information about current developments in the study of medicinal plants recognized for their antiurolithiatic properties. Researchers may find this article useful in identifying the primary compounds or herbal products that exhibit urolithiatic activity.