Evaluation of Anti-inflammatory and Analgesic Activities of Cymbopogon citratus In vivo-Polyphenols Contribution

Garcia, Rita; Ferreira, João Pinto; Costa, Gustavo; Santos, Telmo N; Branco, Fábio; Caramona, Margarida; Carvalho, Rui de; Dinis, Alexandra; Batista, Maria Teresa; Castel‐Branco, Margarida; Figueiredo, Isabel V.

doi:10.3923/rjmp.2015.1.13

Cited by 19 publications

(7 citation statements)

References 31 publications

(41 reference statements)

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“… 26 Furthermore, C citratus was investigated for its analgesic and antipyretic properties, and previous research has suggested that the essential oil from C citratus displayed strong analgesic and antipyretic properties both in central and peripheral analgesic activities. 26 , 27 C hystrix is another ingredient whose chemical composition in essential oil was reported, which dominantly contained citronella (citronellal, citronellol, and geraniol). 28 Citronella, which is commonly used as an effective insect repellent, also exhibited analgesic and anti-inflammatory properties.…”

Section: Discussionmentioning

confidence: 99%

The Distinction of Hot Herbal Compress, Hot Compress, and Topical Diclofenac as Myofascial Pain Syndrome Treatment

Boonruab

Nimpitakpong

Damjuti

2018

J Evid Based Complementary Altern Med

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This randomized controlled trial aimed to investigate the distinctness after treatment among hot herbal compress, hot compress, and topical diclofenac. The registrants were equally divided into groups and received the different treatments including hot herbal compress, hot compress, and topical diclofenac group, which served as the control group. After treatment courses, Visual Analog Scale and 36-Item Short Form Health survey were, respectively, used to establish the level of pain intensity and quality of life. In addition, cervical range of motion and pressure pain threshold were also examined to identify the motional effects. All treatments showed significantly decreased level of pain intensity and increased cervical range of motion, while the intervention groups exhibited extraordinary capability compared with the topical diclofenac group in pressure pain threshold and quality of life. In summary, hot herbal compress holds promise to be an efficacious treatment parallel to hot compress and topical diclofenac.

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Section: Discussionmentioning

confidence: 99%

The Distinction of Hot Herbal Compress, Hot Compress, and Topical Diclofenac as Myofascial Pain Syndrome Treatment

Boonruab

Nimpitakpong

Damjuti

2018

J Evid Based Complementary Altern Med

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“…Essential oil of C. limon exhibited anti-inflammatory effects by reducing cell migration, cytokine production and protein extravasation induced by carrageena (Amorim et al, 2016). Garcia et al (2015) demonstrated the anti-inflammatory and analgesic properties of C. citratus. Z. officinale essential oil contains fragrant compounds like zingiberene, curcumene, camphene, bisabolene, citral and linalool (Mpondo et al, 2017).…”

Section: Discussionmentioning

confidence: 95%

Traditional knowledge of plants used against upper respiratory tract affections in the Littoral Region of Cameroon

Ngotta¹,

Doumbe²,

Nnanga³

et al. 2023

J. Med. Plants Res.

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Traditional medicine is used by people as an alternative to orthodox drugs to treat respiratory infections. The aim of this research was to document traditional recipes used in the treatment of upper respiratory tract infections such as pharyngitis, cold, and sinusitis in peri-urban and rural areas of the Littoral Region of Cameroon. Ethnobotanical surveys were carried out using semi-structured interview model in French or Cameroonian local languages. They were distributed to 115 people. The respondents were both male and female, 20 years old and above, and belonged to seven ethnic groups. Data on plant species and the recipes used against upper respiratory tract infections were collected from the respondents. Plant parts used and methods of preparation were also provided by the respondents. The most abundant ethnic group (56 individuals) was Sawa, followed by Bassa (27) and Bamileke (23). The Lamiaceae family had the highest number of species (06), and Ocimum gratissimum was the most valuable species with 49 citations. Leaf was the main part used (69.94%), and decoction (39.16%) and trituration (38.11%) were the most popular preparation methods. This study has shown the essential role of traditional pharmacopoeia in the treatment of respiratory infections.

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“…The inflammatory mediator NO is derived from the amino acid L-arginine by the iNOS enzyme. Drugs that can inhibit NO production can treat acute and chronic inflammatory symptoms (15,16).…”

Section: Discussionmentioning

confidence: 99%

In vitro evaluation of selligueain A effects on the proinﬂammatory mediators production in RAW264.7 murine macrophages

Suwandi

Rostnawati

Muchtaridi

et al. 2021

J Herbmed Pharmacol

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Introduction: Selligueain A derived from the roots of Polypodium feei was shown to have anti-inflammatory activity, which was tested in vivo on the rats’ paw edema induced by carrageenan. The aim of this study was to evaluate the anti-inflammatory mechanism of selligueain A in vitro against the production of pro-inflammatory mediators. Methods: In this study, RAW264.7 cells were used as an inflammatory cell model, and observations were made on the inflammatory mediators nitric oxide (NO), inducible nitric oxide synthase (iNOS), and tumour necrosis factor-α (TNF-α). The NO concentration was measured by the Griess reaction, and the iNOS enzyme and the TNF-α concentrations were determined by the ELISA method. Cell viability was assessed by the [3-(4,5-dimethylthiazol-2yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium] (MTS) test. Results: Selligueain A at concentrations of 100 and 150 µM suppressed the production of NO, iNOS, and TNF-α in RAW264.7 cells stimulated by lipopolysaccharide (LPS). The concentration of 150 µM showed the highest inhibition of NO, iNOS, and TNF-α mediators with the percentage inhibition of 64.85, 55.01, and 48.54%, respectively. Conclusion: This study shows that selligueain A has anti-inflammatory activity through inhibition of NO, iNOS, and TNF-α production in RAW264.7 macrophage cells.

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Evaluation of Anti-inflammatory and Analgesic Activities of Cymbopogon citratus In vivo-Polyphenols Contribution

Cited by 19 publications

References 31 publications

The Distinction of Hot Herbal Compress, Hot Compress, and Topical Diclofenac as Myofascial Pain Syndrome Treatment

The Distinction of Hot Herbal Compress, Hot Compress, and Topical Diclofenac as Myofascial Pain Syndrome Treatment

Traditional knowledge of plants used against upper respiratory tract affections in the Littoral Region of Cameroon

In vitro evaluation of selligueain A effects on the proinﬂammatory mediators production in RAW264.7 murine macrophages

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