Evaluation of anti-diarrhoeal activity in seed extracts of Mangifera indica

Sairam, K; Hemalatha, S; Kumar, Ashok; Srinivasan, T.; Ganesh, Jai; Shankar, M.; Venkataraman, Satchi

doi:10.1016/s0378-8741(02)00250-7

Cited by 94 publications

(53 citation statements)

References 8 publications

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“…It is also a popular antidiarrhoeal medicinal plant in Guianas (DeFilipps, 2004), Kenya (Njoroge & Kibunga, 2007) and Nepal (Joshi & Joshi, 2000). Seed kernel extracts of Mangifera indica showed positive antidiarrhoeal activity against Proteus vulgaris and Staphylococcus aureus (Sairam et al, 2003), and on castor oil induced diarrhoea in Swiss albino mice (Rajan et al, 2012). According to Neuwinger (1994), bark or root decoction of Ficus sur is taken orally or as an enema for diarrhoea in Ghana.…”

Section: Resultsmentioning

confidence: 99%

Treatment of Diarrhoea Using Traditional Medicines: Contemporary Research in South Africa and Zimbabwe

Maroyi¹

2016

Afr J Tradit Complement Altern Med

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Background: Gastrointestinal disorders, diarrhoea in particular remain a major concern in South Africa and Zimbabwe resulting in high mortality rates when left untreated. This investigation was aimed at documenting herbal medicines used in the treatment of diarrhoea in South Africa and Zimbabwe. Materials and Methods: A review of literature on plant species used as remedies for diarrhoea in South Africa and Zimbabwe was undertaken by the use of different electronic databases such as Google Scholar, ScienceDirect, Scopus as well as library searches at the University of Fort Hare, South Africa and the National Herbarium of Zimbabwe (SRGH) in Harare, Zimbabwe. Results: This study reported ten plant species most widely used to treat diarrhoea in South Africa and Zimbabwe. Of the lot, Sclerocarya birrea (A. Rich.) Hochst. was the most popular medicinal plant used as antidiarrhoeal remedy (11 literature citations) in South Africa and Zimbabwe, followed by Elephantorrhiza elephantina (Burch.) Skeels and Schotia brachypetala Sond. with eight literature citations each. The roots (47.4%) are the most frequently used plant parts, followed by bark (26.3%), leaves (21.1%) and rhizomes (5.3%). Conclusion:The documented antidiarrhoeal activities of this repository of selected plant species against diarrhoea causing agents such as rotavirus, Escherichia coli, Shigella, Campylobacter, Giardia, Entamoeba histolytica, Salmonella, Yersinia and Vibrio cholerae calls for further investigation aimed at isolating phytochemical compounds responsible for antidiarrhoeal activities, their mode of action, and also establish their safety and efficacy. This cross-cultural acceptance of antidiarrhoeal herbal medicines and the use of the same plant species in different geographical zones serve as an indication of the importance of herbal medicines in primary healthcare of local communities.

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Section: Resultsmentioning

confidence: 99%

Treatment of Diarrhoea Using Traditional Medicines: Contemporary Research in South Africa and Zimbabwe

Maroyi¹

2016

Afr J Tradit Complement Altern Med

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“…Aqueous extract of M. indica inhibited the growth of S. aureus and Proteus vulgaris [25]. Gallotannins were extracted from M. indica kernels with aqueous acetone and purified using analytical high-performance liquid chromatography and mass spectrometry confirmed the presence of hydrolyzable tannins with a degree of galloylation ranging from 4 to 9 and additionally revealed the presence of deca-, undeca-, and dodeca-O-galloylglucose with antibacterial activity, as evidenced from the agar spot and critical dilution assays [26][27][28].…”

Section: Discussionmentioning

confidence: 97%

Anti-enteric bacterial activity of the traditional medicinal plants of Kanyakumari coast, Tamilnadu, India

Rajan¹,

Suvetha²,

Thirunalasundari³

et al. 2015

J Coast Life Med

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“…Blood dysentery (Pahan) Anti-diarrheal activity reported in seeds (Sairam et al, 2003); antiinflammatory effect of aqueous extract of plant in experimental colitis (Márquez et al, 2010).…”

Section: Mangifera Indicamentioning

confidence: 99%

Survey and scientific evaluation of medicinal plants used by the Pahan and Teli tribal communities of Natore district, Bangladesh

Rahmatullah

Khatun

Hasan

et al. 2012

Afr. J. Trad. Compl. Alt. Med.

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The Pahans and the Telis are two of the smallest indigenous communities in Bangladesh. The Pahans, numbering about 14,000 people are widely scattered in several northern districts of the country, while the Telis are such a small community that nothing has been reported on their numbers and lifestyle. Both tribes are on the verge of disappearance. One each of the Pahan and the Teli community was located after much search in two adjoining villages of Natore district, Bangladesh. Since the tribes were found to still depend on their traditional medicinal practitioners for treatment of ailments, it was the objective of the present study to document their traditional usage of medicinal plants and to evaluate such plants against modern research-based pharmacological activity studies on these plants. Interviews were conducted of the practitioners of the Pahan and Teli community of Natore district with the help of a semi-structured questionnaire and using the guided field-walk method. Plant specimens as pointed out by the practitioners were collected and pressed on the field and identification completed at the Bangladesh National Herbarium. The Pahan tribal practitioners used 13 plants distributed into 9 families for treatment of 14 different ailments. The Teli tribal practitioner used 15 plants divided into 14 families for treatment of 17 different ailments. Eight out of the thirteen plants used by the Pahan tribal practitioner (61.5%) had reported relevant pharmacological activities in the scientific literature, while six out of the fifteen plants used by the Teli tribal practitioners (40%) had such relevant pharmacological activities in accordance with their usage. The medicinal plants used by the Pahans and Telis warrant further scientific studies toward discovery of lead compounds and efficacious drugs and the documentation and protection of the traditional medical knowledge held by these tribes. .

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Evaluation of anti-diarrhoeal activity in seed extracts of Mangifera indica

Cited by 94 publications

References 8 publications

Treatment of Diarrhoea Using Traditional Medicines: Contemporary Research in South Africa and Zimbabwe

Treatment of Diarrhoea Using Traditional Medicines: Contemporary Research in South Africa and Zimbabwe

Anti-enteric bacterial activity of the traditional medicinal plants of Kanyakumari coast, Tamilnadu, India

Survey and scientific evaluation of medicinal plants used by the Pahan and Teli tribal communities of Natore district, Bangladesh

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