Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography

He, Wenwen; Zhu, Xiangjia; Wolff, Don; Zhao, Zhennan; Sun, Xinghuai; Lu, Yi

doi:10.1155/2016/8656301

Cited by 7 publications

(4 citation statements)

References 24 publications

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“…Based on the authors' knowledge, this is the first time that a novel patient‐oriented procedure is implemented for the comparative analysis of different GDDs. Patient‐specific approach is important since geometrical dimensions like AC volume, width or depth, iris length, and AH inlet width vary from patient to patient and, consequently, affect the heat and mass transfer parameters inside the AC of eye . The present numerical procedure is able to reproduce the exact dimensions of AC of a specific patient, by reconstruction of the 3D computational domain of the anterior segment of the eye from the stacks of tomographic images, received from medical doctors.…”

Section: Introductionmentioning

confidence: 99%

“…Patient-specific approach is important since geometrical dimensions like AC volume, width or depth, iris length, and AH inlet width vary from patient to patient and, consequently, affect the heat and mass transfer parameters inside the AC of eye. 24 The present numerical procedure is able to reproduce the exact dimensions of AC of a specific patient, by reconstruction of the 3D computational domain of the anterior segment of the eye from the stacks of tomographic images, received from medical doctors. Moreover, the present procedure takes into account the model calibration on the basis of preoperative IOP value measured from clinical trials on a specific patient.…”

Section: Introductionmentioning

confidence: 99%

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A novel patient‐oriented numerical procedure for glaucoma drainage devices

Mauro

Massarotti

Mohamed

et al. 2018

Numer Methods Biomed Eng

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The present work analyses the performance of four glaucoma drainage devices, by means of a novel patient-oriented numerical procedure. The procedure is based on the three-dimensional geometry reconstruction from the stacks of tomographic images of a human eye, at different angles, on meshing and on thermo-fluid dynamics modelling activities, carried out on the reconstructed computational domain. The current three-dimensional eye model considers anterior chamber (AC), trabecular meshwork, Schlemm's canal, and collector channels, making use of generalised porous medium approach for modelling ocular porous tissue and cavities. The intraocular pressure (IOP) management inside AC of human eye is analysed, by comparing the results obtained for four drainage devices implanted in a human eye for glaucoma treatment, ie, ExPRESS shunt, iStent inject, SOLX gold micro shunt, and the novel silicon shunt device. The numerical results allow predicting the effects of the installation of these implants on human eyes, in terms of IOP decrease, aqueous humour velocity, pressure, friction coefficient, and local Nusselt number, pointing out the clear distinction between pre-operative and post-operative eye conditions for different glaucoma surgical techniques.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A novel patient‐oriented numerical procedure for glaucoma drainage devices

Mauro

Massarotti

Mohamed

et al. 2018

Numer Methods Biomed Eng

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“…A new biometer using swept-source (SS) optical coherence tomography (OCT) was recently developed [ 9 ]. SSOCT is a Fourier-domain OCT, and the wavelength of the light source is turned in rapid cycles to scan the eye [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Changes in the anterior segment after cycloplegia with a biometer using swept-source optical coherence tomography

2017

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The aim of this study was to investigate changes in the anterior segment of the eye after cycloplegia. A biometer combined with swept-source optical coherence tomography (SSOCT) was used for measurements. Patients with strabismus or amblyopia who underwent cycloplegia were included. The axial length, central corneal thickness, anterior chamber depth, and lens thickness were measured with the biometer–SSOCT system before and after cycloplegia. Altogether, 10 eyes of 10 patients (mean age 7.20 ± 3.08 years, range 4–14 years) were evaluated. The mean measurements before cycloplegia were 22.75 ± 0.96 mm axial length, 516 ± 33 μm central corneal thickness, 3.40 ± 0.21 mm anterior chamber depth, and 3.77 ± 0.26 mm lens thickness. The corresponding values after cycloplegia were 22.75 ± 0.95 mm, 519 ± 34 μm, 3.68 ± 0.16 mm, and 3.42 ± 0.20 mm, respectively. The mean lens thickness had significantly decreased (P < 0.001) after cycloplegia, and the mean anterior chamber depth had significantly increased (P < 0.001). The means of the axial length (P = 0.66) and central corneal thickness (P = 0.17) had not changed significantly. The change in lens thickness was significantly correlated with the change in anterior chamber depth (r = −0.73, P = 0.02). The new biometer–SSOCT combination proved useful for accurately detecting changes in the anterior segment of the eye after cycloplegia in pediatric patients. The biometer’s measurements indicated increased anterior chamber depth and decreased lens thickness after cycloplegia. The anterior chamber depth increased relative to the decrease in lens thickness.

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“…[ 16 ] Some researchers used the Swept-Source Optical Coherence Tomography (SS-OCT) to measure the anterior chamber volume of cataract patients, with a lower (139.80 ± 38.21 mm 3 ) anterior chamber volume than our emmetropic group (183.7 ± 37.5 mm 3 ). [ 17 ] The reasons for the above-mentioned differences, except for the participants in their study(66.48 ± 10.57 years old) were much older than ours, the 3D resolution and accuracy of the OCT might need to be considered. Compare to the computed tomography (CT), MRI avoids health risks associated with ionising radiation found in routine X-rays and CT scans.…”

Section: Discussionmentioning

confidence: 69%

Quantitative analysis with volume rendering of pathological myopic eyes by high-resolution three-dimensional magnetic resonance imaging

Zhou

Chen

et al. 2020

Medicine

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Discovering a relationship between axial length and vitreous volume would be helpful since the axial length is easier to measure than magnetic resonance imaging (MRI) parameters. This study aimed to analyze the topography of human eyes with pathological myopia through volume rendering images by high-resolution 3D-MRI and to establish a model to estimate the vitreous volume. This was a retrospective, non-randomized, controlled study of patients evaluated at Tongren Hospital from July 7, 2007 to December 12, 2018. The controls were emmetropic volunteers. All participants underwent ophthalmic examinations. Axial length was measured with an IOL Master. High-resolution 3D MRI and volume rendering was utilized for all the eyes. Logistic regression was used to establish a model to predict the vitreous volume. A total of 280 emmetropic eyes and 290 eyes with pathological myopia were included. Males represented 60.7% and 65.5% of the individuals. The mean axial lengths of those two groups were 23.1 ± 0.8 mm (95%CI: 22.7–23.4 mm) and 28.3 ± 2.2 mm (95%CI: 27.5–29.2 mm), respectively ( P < .001). The regression model in the pathological myopic group for calculating the vitreous volume according to the axial length was: Vitreous volume = 546.27 × axial length − 6977.12. The regression model in the emmetropic group for calculating the vitreous volume according to the axial length was: Vitreous volume = 458.35 × axial length − 6331.14 ( R 2 = 0.360, P = .001). Elongation of the axial length is involved in eyeball enlargement in pathological myopic eyes. Measurement of the axial length could be recommended for the estimation of the vitreous volume during vitrectomy if vitreous cavity filling is needed.

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Evaluation of Anterior Chamber Volume in Cataract Patients with Swept-Source Optical Coherence Tomography

Cited by 7 publications

References 24 publications

A novel patient‐oriented numerical procedure for glaucoma drainage devices

A novel patient‐oriented numerical procedure for glaucoma drainage devices

Changes in the anterior segment after cycloplegia with a biometer using swept-source optical coherence tomography

Quantitative analysis with volume rendering of pathological myopic eyes by high-resolution three-dimensional magnetic resonance imaging

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