Evaluation of angle-to-angle and spur-to-spur using swept source optical coherence tomography in different refractive error

Abstract

Purpose To measure angle-to-angle (ATA) and spur-to-spur (STS) distances along six meridians using swept-source optical coherence tomography (SS-OCT) and compare with horizontal white-to-white (WTW) distance in different refractive error. Methods Overall, 126 eyes were assessed with the Anterion SS-OCT (Heidelberg Engineering, Heidelberg, Germany). ATA and STS distances were obtained using SS-OCT at 0, 30, 60, 90, 120, and 150 degrees. WTW was measured at 0 degree with built-in infrared camera. One way ANOVA test, pearson correlation coefficient, and stepwise multivariate regression analysis were used to compare ATA and STS distances with age, anterior chamber depth (ACD), axial length (AL), and simulated keratometric values (Sim K) in different refractive error groups. Results The mean MRSE refraction was +0.05 ± 0.23 D in the emmetropic group (41 eyes), -3.42 ± 3.04 D in the myopic group (44 eyes), and +1.33 ± 0.64 D in the hyperopic group (31 eyes). There was no statistical difference in the WTW of the emmetropic (11.62 ± 0.44 mm), myopic (11.79 ± 0.46 mm), and hyperopic groups (11.80 ± 0.49 mm) using one-way ANOVA (p = 0.007). ATA and STS were vertically oval in all groups. The correlation between ATA, STS and age, ACD, AL, and K values showed different significance for each meridian according to the refractive error. ATA increased as the horizontal WTW, ACD, and AL increased and Sim K decreased. STS shows relatively smaller explanatory power than ATA in the stepwise multivariate regression analysis. Conclusions This study is the first to analyze the relationship between ATA and STS compared to WTW by different refractive error. The difference between the horizontally oval WTW and vertically oval anterior chamber can be large, especially in myopia. ATA showed a greater positive correlation than STS with AL and ACD.

Diagnostic Validation of the Screening Corneal Objective Risk of Ectasia Analyzer Evaluated by Swept Source Optical Coherence Tomography for Keratoconus in an Asian Population

“…The new SS-OCT anterior segment device (Anterion ® , Heidelberg Engineering, Heidelberg, Germany) has been clinically proven to be useful in the evaluation of anterior segment [19,20], cataract [21], and glaucoma diseases [22]. The SS-OCT method is considered more advantageous for the topographic and tomographic evaluation of the ectatic cornea than the conventional Placido type or Scheimpflug method, owing to its higher number of radial scans, shorter scan times, and real-time eye tracking system, which detects eye movement and the corneal vertex [23].…”