Evaluation of analgesic effect of Gentamicin in thermally induced pain models in rats and mice

Ponnaluri, Raghunatha Rao; Kolasani, Bhanu Prakash; Mudium, Raghunandan

doi:10.5455/njppp.2017.7.0821723092016

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Hot Plate Test1

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2019

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“…One of the important methods of assessment of analgesic activity is the hot plate test in mice (Ponnaluri et al, 2017;Upasani et al, 2009). Test compounds and aspirin (standard drug) were orally administered at a dose of 10 mg/kg as a suspension in 0.5 ml of 0.5% sodium carboxymethyl cellulose (vehicle) solution.…”

Section: Hot Plate Testmentioning

confidence: 99%

Synthesis, characterization and pharmacological activity of new 2- imino –thiazolidine-4-one derivatives

Alwiswasy¹,

M²,

Hameed³

2019

ijrps

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A new 2-iminothiazolidin-4-ones compound and its derivatives were synthesized and characterized by FT-IR, CHN, and 1HNMR techniques. The target compounds were assessed for their anti-inflammatory and analgesic activities, and the study was performed using Swiss albino mice (25-30 g) for investigation. A hind edema model caused by , while the analgesic activity was assessed using an acetic acid-induced writhing and a hot plate test evaluated the anti-inflammatory activity.

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Section: Hot Plate Testmentioning

confidence: 99%