The objective was to investigate the influence of grade and surface topography of commercially pure titanium (Cp-Ti) on fatigue properties evaluated via staircase method. Cp-Ti grades 2 and 4 were roughened by shot blasting and acid etching, and compared with machined specimens. Yield force under static loading for Cp-Ti grades 2 and 4 were 672±51 and 1,088±93 N for machined and 724±99 and 1,118±96 N for roughened group. Yield force under cyclic loading for Cp-Ti grades 2 and 4 decreased 27 and 40% compared to static loading. Cp-Ti grade 4 demonstrated significantly greater decrease in yield force after cyclic loading; however surface topography had no effect.