Evaluation of amylopectin clusters and their interaction with nonionic surfactants

Miranda, Jacques Antonio de; Cacita, Natacha; Okano, Laura Tiemi

doi:10.1016/j.colsurfb.2007.05.014

Cited by 17 publications

(12 citation statements)

References 38 publications

(67 reference statements)

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“…Limited experimental evidence showed that amylopectin can interact with flavor compounds, surfactants, emulsifiers, lactone and lipids (Arvisenet, Voilley, & Cayot, 2002;de Miranda, Cacita, & Okano, 2007;Eliasson, 1994;Guraya, Kadan, & Champagne, 1997;Heinemann, Escher, & Conde-Petit, 2003;Huang & White, 1993;Villwock, Eliasson, Silverio, & BeMiller, 1999). Heinemann et al (2003) proposed that waxy potato starch can form V 6I helical complex with d-lactone based on the XRD diffraction results.…”

Section: Introductionmentioning

confidence: 98%

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

et al. 2016

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Section: Introductionmentioning

confidence: 98%

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

et al. 2016

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“…[24][25][26][27] In contrast to amylopectin, the fraction of branching units for glycogen is higher at 8%, whereas the value is approximately 5% for amylopectin. [25][26][27] Additionally, the weight average molecular weight (M w ) of glycogen (10 6 −10 7 g/mol) is usually smaller than that of amylopectin (10 6 −10 8 g/mol). [24][25][26] We recently reported that both hyperbranched cationic amylopectin and glycogen derivatives conjugated with 3-(dimethylamino)-1-propylamine (named as DMAPA-Amp and DMAPA-Glyp, respectively; Figure 1) exhibited good blood compatibility and low cytotoxicity, and could effectively deliver plasmid DNA in vitro.…”

Section: Introductionmentioning

confidence: 98%

“…Amylopectin and glycogen are naturally hyperbranched polysaccharides with nontoxicity and good biocompatibility, and they are also biodegradable. [24][25][26][27] Both of them are composed of α-D-(1→4) glucose units of the linear chains, which are interlinked by α-D-(1→6) glycosidic linkage forming the branched structure. [24][25][26][27] In contrast to amylopectin, the fraction of branching units for glycogen is higher at 8%, whereas the value is approximately 5% for amylopectin.…”

Section: Introductionmentioning

confidence: 99%

“…[24][25][26][27] Both of them are composed of α-D-(1→4) glucose units of the linear chains, which are interlinked by α-D-(1→6) glycosidic linkage forming the branched structure. [24][25][26][27] In contrast to amylopectin, the fraction of branching units for glycogen is higher at 8%, whereas the value is approximately 5% for amylopectin. [25][26][27] Additionally, the weight average molecular weight (M w ) of glycogen (10 6 −10 7 g/mol) is usually smaller than that of amylopectin (10 6 −10 8 g/mol).…”

Section: Introductionmentioning

confidence: 99%

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Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles

Liu¹,

Gong²,

Zeng³

et al. 2015

IJN

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A hyperbranched cationic polysaccharide derivative-mediated small interfering (si)RNA interference strategy was proposed to inhibit nuclear transcription factor-kappa B (NF-κB) activation in human retinal pigment epithelial (hRPE) cells for the gene therapy of diabetic retinopathy. Two hyperbranched cationic polysaccharide derivatives containing the same amount of cationic residues, but with different branching structures and molecular weights, including 3-(dimethylamino)-1-propylamine-conjugated glycogen (DMAPA-Glyp) and amylopectin (DMAPA-Amp) derivatives, were developed for the efficient delivery of NF-κB siRNA into hRPE cells. The DMAPA-Glyp derivative showed lower toxicity against hRPE cells. Furthermore, the DMAPA-Glyp derivative more readily condensed siRNA and then formed the nanoparticles attributed to its higher branching architecture when compared to the DMAPA-Amp derivative. Both DMAPA-Glyp/siRNA and DMAPA-Amp/siRNA nanoparticles were able to protect siRNA from degradation by nuclease in 25% fetal bovine serum. The particle sizes of the DMAPA-Glyp/siRNA nanoparticles (70–120 nm) were smaller than those of the DMAPA-Amp/siRNA nanoparticles (130–180 nm) due to the higher branching architecture and lower molecular weight of the DMAPA-Glyp derivative. In addition, the zeta potentials of the DMAPA-Glyp/siRNA nanoparticles were higher than those of the DMAPA-Glyp/siRNA nanoparticles. As a result, siRNA was much more efficiently transferred into hRPE cells using the DMAPA-Glyp/siRNA nanoparticles rather than the DMAPA-Amp/siRNA nanoparticles. This led to significantly high levels of suppression on the expression levels of NF-κB p65 messenger RNA and protein in the cells transfected with DMAPA-Glyp/siRNA nanoparticles. This work provides a potential approach to promote hyperbranched polysaccharide derivatives as nonviral siRNA vectors for the inhibition of NF-κB activation in hRPE cells.

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“…Em nosso laboratório de pesquisa, resultados de um trabalho de Doutorado (Miranda, Cacita & Okano, 2007;Miranda, 2008) do espectro do pireno nas soluções de amilopectina revelaram que quando a sonda fotofísica é aquecida junto com o biopolímero há a formação de agregados. A adição de tensoativo não-iônico à solução de amilopectina promove a saída do pireno para um ambiente mais polar, aumentando a intensidade da relação excímero/monômero do pireno.…”

Section: Composição Estrutura E Propriedadesunclassified

Síntese e caracterização da carboximetil amilopectina com vários graus de substituição

Riul¹

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Agradeço primeiramente a Deus por tornar menos penoso todos os meus caminhos. E que ao fim da minha jornada, que eu possa ter um espírito mais evoluído em amor e sabedoria. A minha família, pela constante dedicação, carinho e apoio. Gostaria de agradecer também minha namorada Aline pelo amor, paciência e companheirismo durante todos esses anos. A professora Laura Tiemi Okano, pela orientação, amizade e apoio. E por contribuir na minha formação como pessoa.

show abstract

Evaluation of amylopectin clusters and their interaction with nonionic surfactants

Cited by 17 publications

References 38 publications

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles

Síntese e caracterização da carboximetil amilopectina com vários graus de substituição

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Evaluation of amylopectin clusters and their interaction with nonionic surfactants

Cited by 17 publications

References 38 publications

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

Effect of fatty acids on functional properties of normal wheat and waxy wheat starches: A structural basis

Efficient delivery of NF-&kappa;B siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles

Síntese e caracterização da carboximetil amilopectina com vários graus de substituição

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Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles