General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms Results: Fourty-two cats were included. Thirty-six cats (87.5%) had an extrahepatic CPSS and six (14.3%) had an intrahepatic CPSS. Pre-operatively, mean cell volume (MCV) and mean cell haemoglobin (MCH) were below the reference interval in 32 (76.2%) and 31 (73.8%) cats respectively. Red blood cell count (RBC) and mean cell haemoglobin concentration (MCHC) were above the reference interval in 10 (23.8%) and eight (19.1%) cats respectively. Postoperatively, there were significant increases in HCT (P = 0.044), MCV (P = 0.008) and MCH (P = 0.002). Despite the significant increase in MCV post-operatively, the median MCV post-operatively was below the reference interval indicating persistence of microcytosis. Preoperatively, PT was above the upper reference interval in 14 cats (87.5%), and aPTT was above the upper reference interval in 11 cats (68.7%). No cat demonstrated a peri-operative clinical bleeding complication.
Haematology and Coagulation Profiles in Cats with Congenital Portosystemic Shunts
Conclusions:Cats with a CPSS are likely to present with a microcytosis, but rarely present with anaemia, leukocytosis or thrombocytopenia. Surgical attenuation of the CPSS results in a significant increase in the HCT and MCV. Coagulation profiles in cats with a CPSS are likely to be prolonged, irrespective of shunt type, but do not appear to be associated with an increased risk of clinical bleeding.MANUSCRIPT