Evaluation of adhesion capacity, cell surface traits and immunomodulatory activity of presumptive probiotic Lactobacillus strains

Kotzamanidis, Christos; Kourelis, Andreas; Litopoulou-Tzanetaki, E.; Tzanetakis, N.; Yiangou, Minas

doi:10.1016/j.ijfoodmicro.2010.04.004

Cited by 142 publications

(82 citation statements)

References 47 publications

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“…casei and L . rhamnosus in healthy mice [14,47] and by LGG in healthy rats [48]. However, our findings did not match when TLR4 expression was studied in some pathologies.…”

Section: Discussionmentioning

confidence: 63%

Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life

et al. 2016

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This study aimed to investigate the effect of supplementation with the probiotic Bifidobacterium breve M-16V on the maturation of the intestinal and circulating immune system during suckling. In order to achieve this purpose, neonatal Lewis rats were supplemented with the probiotic strain from the 6th to the 18th day of life. The animals were weighed during the study, and faecal samples were obtained and evaluated daily. On day 19, rats were euthanized and intestinal wash samples, mesenteric lymph node (MLN) cells, splenocytes and intraepithelial lymphocytes (IEL) were obtained. The probiotic supplementation in early life did not modify the growth curve and did not enhance the systemic immune maturation. However, it increased the proportion of cells bearing TLR4 in the MLN and IEL, and enhanced the percentage of the integrin αEβ7+ and CD62L+ cells in the MLN and that of the integrin αEβ7+ cells in the IEL, suggesting an enhancement of the homing process of naïve T lymphocytes to the MLN, and the retention of activated lymphocytes in the intraepithelial compartment. Interestingly, B. breve M-16V enhanced the intestinal IgA synthesis. In conclusion, supplementation with the probiotic strain B. breve M-16V during suckling improves the development of mucosal immunity in early life.

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“…casei and L . rhamnosus in healthy mice [14,47] and by LGG in healthy rats [48]. However, our findings did not match when TLR4 expression was studied in some pathologies.…”

Section: Discussionmentioning

confidence: 63%

Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life

et al. 2016

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“…The pro-and antiinflammatory cytokines and other stress-related signal molecules play a vital role in maintaining the homeostasis of immune and inflammatory responses. Recent studies suggest that some lactobacilli can elicit an anti-inflammatory response (Kotzamanidis et al, 2010), and in previous experiments we showed that L. crispatus modulated the host pro-inflammatory responses against Candida albicans (Rizzo et al, 2013a).…”

Section: Introductionmentioning

confidence: 62%

Lactobacillus crispatus mediates anti-inflammatory cytokine interleukin-10 induction in response to Chlamydia trachomatis infection in vitro

Rizzo

Fiorentino

Buommino

et al. 2015

International Journal of Medical Microbiology

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“…The industrialization of food bio-transformations even increased the economical importance of LAB, as they have a crucial role in the development of the nutritional, organoleptic, hygienic quality, and health improvement of fermented products [1]. Lactobacillus strains isolated from the human intestinal tract or fermented dairy products are generally regarded as safe (GRAS) and have been extensively exploited for their probiotic properties [2]. So far, there is considerable interest in probiotic for a variety of medical conditions, and millions of people around the world consume probiotics daily for pursuit of health and wellness [3].…”

Section: Introductionmentioning

confidence: 99%

Cell surface properties of Lactobacillus salivarius under osmotic stress

Gong

Chen

et al. 2012

Eur Food Res Technol

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The modifications of cell morphology and surface properties of Lactobacillus salivarius under osmotic stress were investigated. When deMan-RogosaSharpe (MRS) medium was supplemented with NaCl (0.8 mol l -1 ), changes in cell size and shape of L. salivarius cells occurred. A higher autoaggregation percentage and a lower hydrophobicity of L. salivarius determined by microbial adhesion to hydrocarbons were observed under osmotic stress. Moreover, coaggregation was strain specific and depended on incubation time as well as growth medium. On the other hand, fatty acid analysis by gas chromatograph-mass spectrometer revealed increases in the ratio of saturated/unsaturated fatty acids and cyclopropaneoctanoic acid, which is a useful way to enhance their osmotic resistance for maintaining the structural and functional integrity of cell membranes.

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Evaluation of adhesion capacity, cell surface traits and immunomodulatory activity of presumptive probiotic Lactobacillus strains

Cited by 142 publications

References 47 publications

Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life

Preclinical Immunomodulation by the Probiotic Bifidobacterium breve M-16V in Early Life

Lactobacillus crispatus mediates anti-inflammatory cytokine interleukin-10 induction in response to Chlamydia trachomatis infection in vitro

Cell surface properties of Lactobacillus salivarius under osmotic stress

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