Evaluation of Acute Central Serous Chorioretinopathy Using Enhanced Depth Imaging Optical Coherence Tomography and Multifocal Electroretinography

Hong, In Hwan; Chang, In Boem; Jeon, Gang Seok; Han, Jae Ryong

doi:10.1159/000516097

Cited by 2 publications

(3 citation statements)

References 26 publications

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“…Previously, we evaluated patients with acute phase CSC using enhanced depth imaging – OCT and mfERG [17]. In this study, we found that the retinal response from mfERG was impaired in the area beyond the SRD, and the degree of SRF was not associated with mfERG dysfunction; only subfoveal choroidal thickness was associated with mfERG dysfunction.…”

Section: Discussionmentioning

confidence: 76%

Multifocal Electroretinography Changes over 12 Months after Resolution of Central Serous Chorioretinopathy: Prospective Observational Study

et al. 2023

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Purpose: To evaluate the changes in retinal function after anatomical resolution of central serous chorioretinopathy by multifocal electroretinography. Design: Prospective observational study. Methods: Thirty-two eyes of 32 patients with unilaterally resolved central serous chorioretinopathy were prospectively studied. Serial multifocal electroretinography examinations were performed at the initial visit for active central serous chorioretinopathy, the time of anatomical resolution (resolved central serous chorioretinopathy), and 3, 6, and 12 months after resolution. The peak amplitudes of the ﬁrst kernel responses were analysed and compared with those in 27 age-matched normal controls. Results: Compared with controls, N1 amplitudes of ring 1–4 and P1 amplitudes of ring 1–3 showed statistically significant reductions at 12 months after the resolution of central serous chorioretinopathy (p<0.05). The multifocal electroretinography amplitude substantially increased at the time of resolution and gradually improved until three months after the resolution of central serous chorioretinopathy Conclusion: Serial examinations with multifocal electroretinography showed that retinal responses increased mostly after the resolution of central serous chorioretinopathy, and this improvement slowly progressed until three months; however, multifocal electroretinography amplitudes remained statistically reduced 12 months after anatomical resolution of central serous chorioretinopathy, indicating the residual functional deficits detected by multifocal electroretinography.

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Section: Discussionmentioning

confidence: 76%

Multifocal Electroretinography Changes over 12 Months after Resolution of Central Serous Chorioretinopathy: Prospective Observational Study

et al. 2023

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“…When it comes to visual function loss, the mechanisms differ between acute and chronic CSC. In acute CSC, due to the retinal layer morphology being largely intact, visual function impairment is caused by the accumulation of SRF [ 4 , 5 , 7 , 23 ]. In contrast, in chronic CSC, visual function loss predominantly arises due to the disruption of the outer retinal layers and RPE [ 11 – 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…This aligns with the findings of a study that showed mfERG impairment within the area of SRF accumulation [ 5 ]. Conversely, several studies have also indicated that mfERG measurements are affected beyond the area of SRF [ 23 , 30 , 31 ].…”

Section: Discussionmentioning

confidence: 99%

Morphological and Functional Correlations in Acute Central Serous Chorioretinopathy

Kiraly,

Šuštar Habjan,

Smrekar

et al. 2024

Doc Ophthalmol

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Purpose We evaluate morphological and functional correlations in patients with acute central serous chorioretinopathy (CSC). Methods A prospective study was conducted on 50 patients with an acute CSC episode lasting less than 3 months. At baseline, assessments included optical coherence tomography (OCT), best-corrected visual acuity (BCVA), contrast sensitivity (CS), microperimetry (MP), and multifocal electroretinography (mfERG). A correlation analysis between OCT morphological parameters (maximal subretinal fluid height (SRF), central retinal thickness (CRT), and macular volume (MV)) and functional parameters was conducted on the affected eye for each patient. Results Among the morphological parameters, SRF showed the strongest correlations with functional parameters (r absolute value range = 0.10–0.70). Weak correlations were observed between BCVA and morphological parameters (r absolute value range = 0.14–0.26). Average retinal sensitivity (MP-A) was the functional parameter displaying the most robust negative correlation with morphological parameters (r absolute value range = 0.61–0.70). In contrast, average contrast sensitivity (CS-A) and mfERG average amplitude density in the first (mfERG-A1) and second (mfERG-A2) ring showed weak to moderate (r absolute value range = 0.35–0.56) yet statistically significantly nonzero correlations. Conclusions SRF and CRT could serve as the most representative morphological proxies for visual function deficit in acute CSC patients. Retinal sensitivity, as measured by MP, may be superior to BCVA in clinical research studies or when an in-depth visual function evaluation is needed.

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Evaluation of Acute Central Serous Chorioretinopathy Using Enhanced Depth Imaging Optical Coherence Tomography and Multifocal Electroretinography

Cited by 2 publications

References 26 publications

Multifocal Electroretinography Changes over 12 Months after Resolution of Central Serous Chorioretinopathy: Prospective Observational Study

Multifocal Electroretinography Changes over 12 Months after Resolution of Central Serous Chorioretinopathy: Prospective Observational Study

Morphological and Functional Correlations in Acute Central Serous Chorioretinopathy

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