Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life

Ricken, Carla Militão; Péder, Silvia Natalia Souza de; Kamikawa, Daniela Suemi; Pieralisi, Nelí; Silva, Mariliani Chicarelli da; Tolentino, Elen de Souza

doi:10.4067/s0718-381x2021000200443

Cited by 2 publications

(8 citation statements)

References 12 publications

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“…Topical capsaicin was applied for a period of 28 days (excluding the washout period of 14 days) in the study by Jørgensen and Pedersen 23 . The capsaicin application duration was the longest at 180 days in the study by Ricken et al 24 . Three weeks continuous capsaicin topical application as mouthwash three times a day was used in the study by Jankovskis and Selga 22 .…”

Section: Discussionmentioning

confidence: 90%

“…Remission of the symptoms of BMS was observed as early as 28 days in the study by Jørgensen and Pedersen 23 . The study by Ricken et al 24 reported remission of symptoms in 50% of the patients and significant improvement in 40% in the first 30 days. Ricken et al 24 also performed evaluation after 180 days and after medication withdrawal, and 60% of the patients reported total absence of BMS symptoms.…”

Section: Discussionmentioning

confidence: 93%

“…Capsaicin was used singly or in combination with other agents. No control was used in the studies by Jørgensen and Pedersen 23 and Ricken et al 24 . Placebo rinse was used in the study by Silvestre et al 25 .…”

Section: Resultsmentioning

confidence: 99%

“…Four studies were included for the final qualitative synthesis of data. None had a randomized design, and all were interventional studies of topical capsaicin application 22 - 25 . Capsaicin was used at concentrations ranging from 0.01% to 0.025% among the included studies.…”

Section: Discussionmentioning

confidence: 99%

“…Capsaicin was used at concentrations ranging from 0.01% to 0.025% among the included studies. Topical application of capsaicin was delivered in gel form in the studies by Jørgensen and Pedersen 23 and Ricken et al 24 and in mouthwash form at a concentration of 0.02% in the studies by Jankovskis and Selga 22 and Silvestre et al 25 . Capsaicin was used alone in three studies 23 - 25 , but was used in conjunction with other agents such as zinc and vitamin B 12 supplements in the study by Jankovskis and Selga 22 .…”

Section: Discussionmentioning

confidence: 99%

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Burning measure for burning mouth syndrome: a systematic review

Tirupathi,

Malothu,

Allaparthi

et al. 2024

JKAOMS

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This current systematic review aimed to evaluate the current evidence on the effect of topical capsaicin application to alleviate symptoms related to burning mouth syndrome (BMS). PubMed, Ovid SP, and Cochrane were searched from 1980 to 2022 to identify relevant literature. A total of 942 titles (PubMed, 84; Ovid SP, 839; Cochrane, 19) was retrieved, of which 936 were excluded based on the title and abstract. A total of 11 studies were further evaluated for full text analysis, of which 7 were excluded. As a result, 4 articles were included for qualitative synthesis of data. Capsaicin as a mouthwash can have potential application in the treatment of symptoms related to burning mouth. The quality of available studies is moderate to low, and a well-designed randomized multicentric study comparing capsaicin with other active agents is planned to obtain more definitive conclusions.

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Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 93%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Burning measure for burning mouth syndrome: a systematic review

Tirupathi,

Malothu,

Allaparthi

et al. 2024

JKAOMS

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A Fitoterapia No Tratamento Da Alveolite: Uma Revisão Sistemática De Literatura

Ferreira Rocha,

Pombo Sudré da Silva,

Nocelle de Almeida

2024

RECIMA21

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Dentre as principais complicações após a extração de dentes permanentes está a alveolite causada pela infecção de microrganismos no alvéolo, que ajudam a desintegrar o coágulo através da fibrinólise. Várias são as modalidades de tratamento para a alveolite; contudo, o uso de antibióticos de forma inadequada pode gerar resistência bacteriana. Os medicamentos extraídos de plantas e seus derivados apresentam grande eficácia no tratamento de feridas, entre elas, a alveolite. Além de disponíveis e baratos, também são considerados seguros, pois raramente provocam reações alérgicas a eles. O objetivo desse estudo foi realizar uma revisão sistemática da literatura sobre o uso de fitoterápicos, plantas medicinais, no tratamento da alveolite. A base de dados utilizada foi o Google Acadêmico com os seguintes termos de busca em inglês: “alveolitis”, “medicinal plant” e “dental extraction” com o intervalo temporal de janeiro de 2000 a agosto de 2023. Dois revisores (1º e 2º autores) avaliaram de forma independente os registros selecionando os artigos que atendiam aos critérios de elegibilidade. Os dados extraídos dos artigos foram planilhados no Excel, contemplando 22 variáveis, entre elas os principais princípios ativos relativos ao tratamento da alveolite. Observou-se que os documentos selecionados geraram uma gama de dados relevantes que poderão ser úteis para direcionar novos estudos.

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Evaluation of a Protocol For Topical Application of Capsaicine Gel 0.025 % in the Management of Burning Mouth Syndrome Correlating its Impact on Quality of Life

Abstract: of a protocol for topical application of capsaicine gel 0.025 % in the management of burning mouth syndrome correlating its impact on quality of life.

Cited by 2 publications

References 12 publications

Burning measure for burning mouth syndrome: a systematic review

Burning measure for burning mouth syndrome: a systematic review

A Fitoterapia No Tratamento Da Alveolite: Uma Revisão Sistemática De Literatura

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