Evaluation of a novel 4D <i>in vivo</i> dosimetry system

Cherpak, Amanda; Ding, W.; Hallil, A; Cygler, Joanna

doi:10.1118/1.3100264

Cited by 38 publications

(57 citation statements)

References 54 publications

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“…Examples are tracking of instruments in surgical interventions,14 guidance of biopsies,15 and motion monitoring in ablation 16 or external beam radiation therapy 17. A review of the technological fundamentals and the clinical applications is given by Franz et al 18.…”

Section: Introductionmentioning

confidence: 99%

Electromagnetic tracking (EMT) technology for improved treatment quality assurance in interstitial brachytherapy

Kellermeier

Herbolzheimer

Kreppner

et al. 2017

J Applied Clin Med Phys

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Electromagnetic Tracking (EMT) is a novel technique for error detection and quality assurance (QA) in interstitial high dose rate brachytherapy (HDR‐iBT). The purpose of this study is to provide a concept for data acquisition developed as part of a clinical evaluation study on the use of EMT during interstitial treatment of breast cancer patients. The stability, accuracy, and precision of EMT‐determined dwell positions were quantified. Dwell position reconstruction based on EMT was investigated on CT table, HDR table and PDR bed to examine the influence on precision and accuracy in a typical clinical workflow. All investigations were performed using a precise PMMA phantom. The track of catheters inserted in that phantom was measured by manually inserting a 5 degree of freedom (DoF) sensor while recording the position of three 6DoF fiducial sensors on the phantom surface to correct motion influences. From the corrected data, dwell positions were reconstructed along the catheter's track. The accuracy of the EMT‐determined dwell positions was quantified by the residual distances to reference dwell positions after using a rigid registration. Precision and accuracy were investigated for different phantom‐table and sensor‐field generator (FG) distances. The measured precision of the EMT‐determined dwell positions was ≤ 0.28 mm (95th percentile). Stability tests showed a drift of 0.03 mm in the first 20 min of use. Sudden shaking of the FG or (large) metallic objects close to the FG degrade the precision. The accuracy with respect to the reference dwell positions was on all clinical tables < 1 mm at 200 mm FG distance and 120 mm phantom‐table distance. Phantom measurements showed that EMT‐determined localization of dwell positions in HDR‐iBT is stable, precise, and sufficiently accurate for clinical assessment. The presented method may be viable for clinical applications in HDR‐iBT, like implant definition, error detection or quantification of uncertainties. Further clinical investigations are needed.

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Section: Introductionmentioning

confidence: 99%

Electromagnetic tracking (EMT) technology for improved treatment quality assurance in interstitial brachytherapy

Kellermeier

Herbolzheimer

Kreppner

et al. 2017

J Applied Clin Med Phys

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“…Diodebased in-vivo dosimetry has been widely explored and reported in the literature [20][21][22][23][24]. Similar investigations have been reported with TLDs [25,26] and with MOSFET dosimeters [27][28][29]. On the other hand OSLDs potential in medical dosimetry [30] was recognized due to their small size suitable for point measurements, high sensitivity, non-destructive readout and reanalysis and the use of relatively simple readers with a high degree of automation.…”

Section: ""% #% #"mentioning

confidence: 80%

Assessment of patient dose in medical processes byin-vivodose measuring devices: A review

Tunçel

2016

EPJ Web Conf.

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"#!# In-vivo dosimetry (IVD) in medicine especially in radiation therapy is a well-established and recommended procedure for the estimation of the dose delivered to a patient during the radiation treatment. It became even more important with the emerging use of new and more complex radiotherapy techniques such as intensity-modulated or image-guided radiation therapy. While IVD has been used in brachytherapy for decades and the initial motivation for performing was mainly to assess doses to organs at risk by direct measurements, it is now possible to calculate 3D for detection of deviations or errors. Invivo dosimeters can be divided into real-time and passive detectors that need some finite time following irradiation for their analysis. They require a calibration against a calibrated ionization chamber in a known radiation field. Most of these detectors have a response that is energy and/or dose rate dependent and consequently require adjustments of the response to account for changes in the actual radiation conditions compared to the calibration situation. Correction factors are therefore necessary to take. Today, the most common dosimeters for patients' dose verification through in-vivo measurements are semiconductor diodes, thermo-luminescent dosimeters, optically stimulated luminescence dosimeters, metal-oxidesemiconductor field-effect transistors and plastic scintillator detectors with small outer diameters.

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“…46,98 The RADPOS probe is 1.3 mm in diameter and can fit inside a Foley catheter or in an interstitial catheter. The probe incorporates a positioning sensor (see Detector positioning technology section) and a radio-opaque marker, both of which are visible on radiographs and aid probe localization procedures based on patient images.…”

Section: Novel Dosimetry Technology Multipoint Dosemetersmentioning

confidence: 99%

“…46,98 The computer-controlled system combines multipoint real-time dosimetry with an electromagnetic positioning device and includes a software program that allows sampling of position and dose rates either manually or automatically in user-defined time intervals. The position coordinates of the detector are determined by monitoring the response of the motion sensor to a pulsed 3D magnetic field generated by a 3D-Guidance™ DC magnetic field transmitter (Ascension Technology Corporation; Burlington, VT).…”

Section: Detector Positioning Technologymentioning

confidence: 99%

In vivodosimetry: trends and prospects for brachytherapy

Kertzscher¹,

Rosenfeld²,

Beddar³

et al. 2014

BJR

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The error types during brachytherapy (BT) treatments and their occurrence rates are not well known. The limited knowledge is partly attributed to the lack of independent verification systems of the treatment progression in the clinical workflow routine. Within the field of in vivo dosimetry (IVD), it is established that real-time IVD can provide efficient error detection and treatment verification. However, it is also recognized that widespread implementations are hampered by the lack of available high-accuracy IVD systems that are straightforward for the clinical staff to use. This article highlights the capabilities of the state-of-the-art IVD technology in the context of error detection and quality assurance (QA) and discusses related prospects of the latest developments within the field. The article emphasizes the main challenges responsible for the limited practice of IVD and provides descriptions on how they can be overcome. Finally, the article suggests a framework for collaborations between BT clinics that implemented IVD on a routine basis and postulates that such collaborations could improve BT QA measures and the knowledge about BT error types and their occurrence rates.

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Evaluation of a novel 4D in vivo dosimetry system

Cited by 38 publications

References 54 publications

Electromagnetic tracking (EMT) technology for improved treatment quality assurance in interstitial brachytherapy

Electromagnetic tracking (EMT) technology for improved treatment quality assurance in interstitial brachytherapy

Assessment of patient dose in medical processes byin-vivodose measuring devices: A review

In vivodosimetry: trends and prospects for brachytherapy

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