Evaluation of a new durable insulin pen with memory function among people with diabetes and healthcare professionals

X, Guo; Vanterpool, Grace; Qvist, Marianne; Bethien, Matthias; Lilleøre, Søren Kruse

doi:10.1517/17425247.2012.671808

Cited by 14 publications

(20 citation statements)

References 38 publications

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“…The studies included research conducted worldwide using ethnically and racially diverse samples and both adult (n=9, 69.2%)35,37–40,42,43,45,46 and adolescent (n=2, 15.4%),34,44 as well as combined age populations (n=2, 15.4%) 36,41. The studies, the devices implemented, and their results are presented in Table 2.…”

Section: Resultsmentioning

confidence: 99%

“…A total of nine studies reported patients’ and clinicians’ attitudes towards the usability, functionality, and impact of devices with dose-memory and combined dose-memory and dose-reminder device functions 37,38,40–46…”

Section: Resultsmentioning

confidence: 99%

“…Guo et al40 found that patients reported feeling considerably more confident managing their daily insulin injections using the NovoPen ® 5 (with dose-memory function) than the HumaPen Luxura™ and ClikSTAR ® (Sanofi-Aventis, Paris, France) (both without dose-memory function) because the NovoPen ® 5 allowed them to review the volume (42%) and time (39%) of their last dose. This was supported by HCPs, with 75% agreeing that the dose-memory device function was particularly valuable for patients who tended to forget to perform injections.…”

Section: Resultsmentioning

confidence: 99%

“…Finally, Guo et al40 found that more patients with diabetes felt “very confident” managing their daily insulin injections using the NovoPen ® 5 compared with their previous device because the visual confirmation of the dose and the audible end-of-dose sound provided reassurance that they had injected the full dose.…”

Section: Resultsmentioning

confidence: 99%

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The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management

Hall¹,

Willgoss²,

Humphrey³

et al. 2014

PPA

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BackgroundAdherence to treatment is an important issue in chronic disease management and an indicator of patients’ ability to self-manage their condition and treatment. Some drug-dispensing and drug-delivery devices have been designed to support patients’ medication-taking behavior by including dose-memory and combined dose-memory and dose-reminder functions, which electronically store, and visually display dose-history information, enabling the patient to review, monitor, and/or be actively reminded about their medication doses.PurposeThis literature review explored the role and impact of these devices on patients’ treatment adherence, confidence with, and self-management of their condition and treatment.Materials and methodsA search of MEDLINE, Embase, and PsycINFO was performed to identify articles published in English from 2003–2013 that studied the effect of devices with dose-memory and combined dose-memory and dose-reminder functions on treatment adherence and users’ (patients, health care professionals [HCPs], and caregivers) confidence, self-management behavior, and attitudes.ResultsThe database searches yielded 940 abstracts from which 13 articles met the inclusion criteria and were retained. Devices with dose-memory and combined dose-memory and dose-reminder functions were found to improve self-reported and electronically monitored treatment adherence in chronic conditions such as asthma, diabetes, and HIV. The ability of the devices to provide dose-history information and active medication reminders was considered valuable in disease management by patients, caregivers, and HCPs. The devices were found to enhance patients’ confidence in, and motivation to manage their medication and condition, and help reduce forgotten or incorrect medication dosing.ConclusionThe incorporation of dose-memory and combined dose-memory and dose-reminder functions in drug-delivery devices can improve patients’ adherence, confidence, and self-management behavior. They can target non-intentional barriers to adherence and can provide a means of improving disease control and clinical outcomes, thereby offering clinical and economic value. This review highlights the importance of conducting further qualitative and quantitative research to further understand the value and impact of these types of devices on patients’ long-term adherence to, and self-management of treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management

Hall¹,

Willgoss²,

Humphrey³

et al. 2014

PPA

View full text Add to dashboard Cite

show abstract

“…This feature has been developed as a safety feature to address user anxiety over a forgotten dose and risk of hypoglycemia through double-dosing. 14,[45][46][47][48] NPE is the only HUP with this feature and records the last dose volume and time (<12 h). 24,40,49 The majority of pediatric users (89%) and parents (94%) rated this feature as very easy or easy to use.…”

Section: Factors Affecting the User Preference For An Hupmentioning

confidence: 99%

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

Klonoff

Nayberg

Stauder

et al. 2016

J Diabetes Sci Technol

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Background: Insulin pens represent a significant technological advancement in diabetes management. While the vast majority have been designed with 1U-dosing increments, improved accuracy and precision facilitated by half-unit increments may be particularly significant in specific patients who are sensitive to insulin. These include patients with low insulin requirements and in those requiring more precise dose adjustments, such as the pediatric patient population. This review summarized functional characteristics of insulin half-unit pens (HUPs) and their effect on user experience. Methods: The literature search was restricted to articles published in English between January 1, 2000, and January 1, 2015. A total of 17 publications met the set criteria and were included in the review. Results: Overall, studies outlined characteristics for 4 insulin HUPs. Based on their functionality, the pens were generally similar and all met the ISO 11608-1 criteria for accuracy. However, some had specific advantageous features in terms of size, weight, design, dialing torque, and injection force. Although limited, the currently available user preference studies in children and adolescents with diabetes and their carers suggest that the selection of an HUP is likely to be influenced by a combination of factors such as these, in addition to the prescribed insulin and dosing regimen. Conclusions: Insulin HUPs are likely to be a key diabetes management tool for patients who are sensitive to insulin; specific pen features may further advance diabetes management in these populations.

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A Systematic Review of Patients’ Perspectives on the Subcutaneous Route of Medication Administration

Ridyard

Dawoud

Tuersley

et al. 2016

Patient

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Evaluation of a new durable insulin pen with memory function among people with diabetes and healthcare professionals

Cited by 14 publications

References 38 publications

The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management

The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

A Systematic Review of Patients’ Perspectives on the Subcutaneous Route of Medication Administration

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Evaluation of a new durable insulin pen with memory function among people with diabetes and healthcare professionals

Cited by 14 publications

References 38 publications

The effect of medical device dose-memory functions on patients&rsquo; adherence to treatment, confidence, and disease self-management

The effect of medical device dose-memory functions on patients&rsquo; adherence to treatment, confidence, and disease self-management

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

A Systematic Review of Patients’ Perspectives on the Subcutaneous Route of Medication Administration

Contact Info

Product

Resources

About

The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management

The effect of medical device dose-memory functions on patients’ adherence to treatment, confidence, and disease self-management