Evaluation of a knitted polytetrafluoroethylene mesh placed intraperitoneally in a New Zealand white rabbit model

Novotný, Tomáš; Jeřábek, Jiří; Veselý, Karel; Staffa, Robert; Dvořák, Martin; Cagaš, Jan

doi:10.1007/s00464-011-2120-4

Cited by 8 publications

(2 citation statements)

References 29 publications

(25 reference statements)

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“…Novotny et al found that polypropylene was comparable with PTFE in terms of biocompatibility when a sample of mesh was implanted intraperitoneally in New Zealand white rabbits. At 90 days post-implantation, the number of inflammatory cells and granuloma formation were seen to be similar [37]. All other studies reviewed by this group found comparable results.…”

Section: Materials Discussionmentioning

confidence: 64%

In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

Kelly¹,

Macdougall²,

Olabisi³

et al. 2016

Int Urogynecol J

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Introduction and hypothesisPolypropylene is a material that is commonly used to treat pelvic floor conditions such as pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Owing to the nature of complications experienced by some patients implanted with either incontinence or prolapse meshes, the biocompatibility of polypropylene has recently been questioned. This literature review considers the in vivo response to polypropylene following implantation in animal models. The specific areas explored in this review are material selection, impact of anatomical location, and the structure, weight and size of polypropylene mesh types.MethodsAll relevant abstracts from original articles investigating the host response of mesh in vivo were reviewed. Papers were obtained and categorised into various mesh material types: polypropylene, polypropylene composites, and other synthetic and biologically derived mesh.ResultsPolypropylene mesh fared well in comparison with other material types in terms of host response. It was found that a lightweight, large-pore mesh is the most appropriate structure.ConclusionThe evidence reviewed shows that polypropylene evokes a less inflammatory or similar host response when compared with other materials used in mesh devices.Electronic supplementary materialThe online version of this article (doi:10.1007/s00192-016-3029-1) contains supplementary material, which is available to authorized users

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Section: Materials Discussionmentioning

confidence: 64%

In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

Kelly¹,

Macdougall²,

Olabisi³

et al. 2016

Int Urogynecol J

View full text Add to dashboard Cite

show abstract

“…Both the groups showed similar results with respect to the factors studied, but after excluding adhesions at the edges, ePTFE fared better with respect to adhesions. Another experimental study by Novotny [10] in rabbits compared the intraperitoneally placed knitted PTFE mesh with PPM. They found fewer adhesions but more shrinkage in the PTFE group.…”

Section: Reports: In Support Of Ppmmentioning

confidence: 99%

Intra Peritoneal Polypropylene Mesh and Newer Meshes in Ventral Hernia Repair: What EBM Says?

Ramakrishna¹,

Lakshman

2012

Indian J Surg

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Incisional hernias and other ventral hernias are common surgical problems. It is estimated that incisional hernia complicates about 2 % to 10 % of laparotomies. Ventral and incisional hernia repairs are among the common surgeries done by a general surgeon. It is proven beyond any doubt that suture repair of these hernias should not be done as recurrence rates are unacceptably high, some series reporting as high as 54 % on long-term follow-up. A prosthetic mesh should always be used in ventral hernia repair (VHR). Now, the polypropylene mesh (PPM) has become the prosthetic mesh of choice in the repair of hernias, including inguinal hernia. However, with the advent of laparoscopic repair where the mesh is placed intraperitoneally, concerns regarding safety of PPM are raised. Newer meshes are introduced, claiming lesser complication rate. Many types of newer meshes are available now. Newer meshes are invariably costlier than PPM by 15-20 times. Is this extra cost worth? We looked in to available literature for an answer.

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Which mesh is appropriate for laparoscopic use? Prevention of adhesions to macroporous mesh, a rabbit model

et al. 2012

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Evaluation of a knitted polytetrafluoroethylene mesh placed intraperitoneally in a New Zealand white rabbit model

Cited by 8 publications

References 29 publications

In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

Intra Peritoneal Polypropylene Mesh and Newer Meshes in Ventral Hernia Repair: What EBM Says?

Which mesh is appropriate for laparoscopic use? Prevention of adhesions to macroporous mesh, a rabbit model

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